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    Article

    GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system

    Pigs are excellent large animal models with several similarities to humans. They provide valuable insights into biomedical research that are otherwise difficult to obtain from rodent models. However, even if m...

    Fuminori Tanihara, Maki Hirata, Zhao Namula, Manita Wittayarat in Molecular Biology Reports (2023)

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    Evaluation of multiple gene targeting in porcine embryos by the CRISPR/Cas9 system using electroporation

    The CRISPR/Cas9 system now allows for unprecedented possibilities of genome editing. However, there are some limitations, including achieving efficient one-step multiple genome targeting to save costs, time, a...

    Maki Hirata, Manita Wittayarat, Zhao Namula, Quynh Anh Le in Molecular Biology Reports (2020)