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Retinoblastoma protein-overexpressing HL60 cells resistant to 1,25-dihydroxyvitamin D3 display increased CDK2 and CDK6 activity and shortened G1 phase

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  1. Article

    Improvement of awareness, treatment and control of hypertension among chronic kidney disease patients in China from 1999 to 2005

    Controlling hypertension is important to protect renal function and prevent cardiovascular disease in chronic kidney disease (CKD) patients. However, data on hypertension awareness, treatment and control among...

    Yu Wang, Luxia Zhang, **aomei Li, Yulan Xu, Min Yang, Jiaqi Qian in Hypertension Research (2009)

  2. Article

    Open Access

    Early decrease in carotid plaque lipid content as assessed by magnetic resonance imaging during treatment of rosuvastatin

    Statin therapy has shown to deplete atherosclerotic plaque lipid content and induce plaque regression. However, how early the plaque lipid depletion can occur with low-density lipoprotein cholesterol (LDL-C) l...

    Ruixue Du, Jianming Cai, Xue-Qiao Zhao, Qing-Jun Wang in BMC Cardiovascular Disorders (2014)

  3. Article

    Open Access

    National trends in hospital length of stay for acute myocardial infarction in China

    China is experiencing increasing burden of acute myocardial infarction (AMI) in the face of limited medical resources. Hospital length of stay (LOS) is an important indicator of resource utilization.

    Qian Li, Zhenqiu Lin, Frederick A Masoudi, **g Li, ** Li in BMC Cardiovascular Disorders (2015)

  4. Article

    Open Access

    Comparison of preoperative evaluation of malignant low-level biliary obstruction using plain magnetic resonance and coronal liver acquisition with volume acceleration technique alone and in combination

    To evaluate the clinical value of plain magnetic resonance (MR) imaging (including magnetic resonance cholangiopancreatography, MRCP) and coronal liver acquisition with volume acceleration (LAVA) technique in ...

    Nana Sun, Qing Xu, **sheng Liu, Wei Liu in European Journal of Medical Research (2015)

  5. Article

    Comparative effectiveness of sildenafil for pulmonary hypertension due to left heart disease with HFrEF

    There is no cure for pulmonary hypertension due to left heart disease (PH-LHD), but the rationale for using sildenafil to treat pulmonary arterial hypertension with heart failure with reduced ejection fraction...

    Rong Jiang, Lan Wang, Chang-Tai Zhu, ** Yuan, Bigyan Pudasaini in Hypertension Research (2015)

  6. Article

    Augmentation of autophagy by atorvastatin via Akt/mTOR pathway in spontaneously hypertensive rats

    Autophagy is activated in hypertension-induced cardiac hypertrophy. However, the mechanisms and significance of an activated autophagy are not clear. This study was designed to determine the role of atorvastat...

    Wei Wang, Hao Wang, Qing-**n Geng, Hua-Ting Wang, Wei Miao in Hypertension Research (2015)

  7. Article

    Open Access

    Treatment of CD20-directed Chimeric Antigen Receptor-modified T cells in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an early phase IIa trial report

    Patients with relapsed or refractory non-Hodgkin lymphoma have a dismal prognosis. Chimeric Antigen Receptor (CAR)-modified T cells (CART cells) that targeted CD20 were effective in a phase I clinical trial fo...

    Wen-ying Zhang, Yao Wang, Ye-lei Guo in Signal Transduction and Targeted Therapy (2016)

  8. Article

    Reversal of right ventricular remodeling by dichloroacetate is related to inhibition of mitochondria-dependent apoptosis

    Most patients with pulmonary arterial hypertension die from right ventricular failure (RVF). Right ventricular (RV) myocardial apoptosis has an important role in RVF and is regulated by the mitochondria. Dichl...

    **ao-Qing Sun, Rui Zhang, Hong-Da Zhang, ** Yuan, **ao-Jian Wang in Hypertension Research (2016)

  9. Article

    Open Access

    Long-term safety and efficacy of CART-20 cells in patients with refractory or relapsed B-cell non-Hodgkin lymphoma: 5-years follow-up results of the phase I and IIa trials

    Wen-ying Zhang, Yang Liu, Yao Wang in Signal Transduction and Targeted Therapy (2017)

  10. Article

    Open Access

    The value of shock index in prediction of cardiogenic shock developed during primary percutaneous coronary intervention

    Shock index(SI) is a conventional predictive marker for haemodynamic state. Its breakpoint varies by different conditions according to previous studies. The current study was performed to evaluate the capabili...

    Zhonghai Wei, Jian Bai, Qing Dai, Han Wu, Shuaihua Qiao in BMC Cardiovascular Disorders (2018)

  11. Article

    Open Access

    Comparison short time discharge with long time discharge following uncomplicated percutaneous coronary intervention for Non-ST elevation myocardial infarction patients

    The rational length of stay following non-complicated percutaneous coronary intervention (PCI) for Non-ST elevation myocardial infarction (NSTEMI) patients remains controversial. Few studies have examined the ...

    Guozhong Wang, Quanming Zhao, Qing Cheng, **aoxia Zhang in BMC Cardiovascular Disorders (2019)

  12. Article

    Open Access

    Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats

    Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function. Cardiac fibroblasts surely influence this process. Besides, macrophage plays an essential role in cardiac r...

    Yan Che, Di-Fei Shen, Zhao-Peng Wang, Ya-Ge ** in BMC Cardiovascular Disorders (2019)

  13. Article

    Open Access

    A novel small-molecule inhibitor of trefoil factor 3 (TFF3) potentiates MEK1/2 inhibition in lung adenocarcinoma

    TFF3 has been identified as a novel biomarker to distinguish between lung adenocarcinoma (ADC) and lung squamous-cell carcinoma (SCC). Herein, we determined the oncogenic functions of TFF3 and demonstrated the...

    Mengyi Zhang, Baocheng Wang, Qing-Yun Chong, Vijay Pandey, Zhirong Guo in Oncogenesis (2019)

  14. Article

    Open Access

    Glycemic control is associated with atrial structural remodeling in patients with type 2 diabetes

    Diabetes mellitus (DM) has been demonstrated to be a strong risk factor for development and perpetuation of atrial fibrillation (AF). However, how DM and glycemic control affect the pathogenesis of AF has not ...

    Qing Wang, **g Wang, Pei Wang, Liaoyuan Wang, Lanting Jia in BMC Cardiovascular Disorders (2019)

  15. Article

    Open Access

    Comparison of transthoracic echocardiography with computed tomography in evaluation of pulmonary veins

    Transesophageal echocardiography may be used to assess pulmonary veins for atrial fibrillation ablation. No study focused on the role of transthoracic echocardiography (TTE) in evaluating the diameter and anat...

    Qing-Qing Dong, Wen-Yi Yang, Ya-** Sun, Qian Zhang in BMC Cardiovascular Disorders (2019)

  16. Article

    Open Access

    Bioinformatic analysis of peripheral blood miRNA of breast cancer patients in relation with anthracycline cardiotoxicity

    The current diagnostic methods and treatments still fail to lower the incidence of anthracycline-induced cardiotoxicity effectively. In this study, we aimed to (1) analyze the cardiotoxicity-related genes afte...

    Wang Yadi, Chen Shurui, Zhang Tong, Chen Suxian, Tong Qing in BMC Cardiovascular Disorders (2020)

  17. Article

    Open Access

    Efficacy and safety of standard and low dose ticagrelor versus clopidogrel in east AsianPatients with chronic total occlusion undergoing percutaneous coronary intervention: a single center retrospective study

    Patients with coronary chronic total occlusion (CTO) require effective antiplatelet therapy after percutaneous coronary intervention (PCI). Ticagrelor has more pronounced platelet inhibition than clopidogrel. ...

    Yong Wang, Hong-wei Zhao, Cheng-fu Wang, **ao-jiao Zhang in BMC Cardiovascular Disorders (2020)

  18. Article

    Open Access

    Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes

    Yi Ching Esther Wan, Tsz Chui Sophia Leung in Signal Transduction and Targeted Therapy (2020)

  19. Article

    Open Access

    Advances in targeted therapy for malignant lymphoma

    The incidence of lymphoma has gradually increased over previous decades, and it ranks among the ten most prevalent cancers worldwide. With the development of targeted therapeutic strategies, though a subset of...

    Li Wang, Wei Qin, Yu-Jia Huo, **ao Li, Qing Shi in Signal Transduction and Targeted Therapy (2020)

  20. Article

    Open Access

    Inhibition of USP14 and UCH37 deubiquitinating activity by b-AP15 as a potential therapy for tumors with p53 deficiency

    Yu-Shui Ma, **ao-Feng Wang, Fei Yu in Signal Transduction and Targeted Therapy (2020)

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