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12 Result(s)

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  1. No Access

    Article

    The Influence of Various Freezing–thawing Methods of Skin on Drug Permeation and Skin Barrier Function

    The selection of skin is crucial for the in vitro permeation test (IVPT). The purpose of this study was to investigate the influence of different freezing–thawing processes on the barrier function of skin and the...

    **nying Wang, Yuanyuan Zhang, Kaili Liang, Xue Meng, Chunyan Ma… in The AAPS Journal (2024)

  2. No Access

    Article

    Biomimetic Antidote Nanoparticles: a Novel Strategy for Chronic Heavy Metal Poisoning

    Chronic lead poisoning has become a major factor in global public health. Chelation therapy is usually used to manage lead poisoning. Dimercaptosuccinic acid (DMSA) is a widely used heavy metal chelation agent...

    Hao Wang, Qing Yao, Wenquan Zhu, Yang Yang, Chunsheng Gao, Cuiyan Han… in AAPS PharmSciTech (2022)

  3. No Access

    Article

    Enhanced Nuclear Accumulation of Doxorubicin Delivered by pH-Triggered Polydopamine-Shelled Mesoporous Silica for Chemo-Photothermal Therapy

    Adequate delivery of therapeutic agents to their intended molecular targets is crucial in tumor therapy. Versatile drug carriers need to overcome the challenges coming from the systemic circulation, membrane b...

    **aoling Wang, Jiangyue Du, Feng Zhou, Qing Ye, Ying Chen, Dujuan Sun… in AAPS PharmSciTech (2022)

  4. No Access

    Article

    Design of a Long-Acting Rivastigmine Transdermal Delivery System: Based on Computational Simulation

    The purpose of our study was using a computational simulation to develop a long-acting patch of rivastigmine (RVS). A range of patch formulations were screened including pressure sensitive adhesive (PSA), phar...

    Xue Han, **gchuan Liu, **aoyue Hu, Wei Wang, Qing Wang in AAPS PharmSciTech (2022)

  5. No Access

    Chapter

    Syngas Production, Storage, Compression and Use in Gas Turbines

    This chapter analyses syngas production through pyrolysis and gasification, its compression and its use in gas turbines. Syngas compression can be performed during or after thermal treatment processes. Importa...

    Minjiao Yang, Hai** Yang, Hewen Zhou… in Production of Biofuels and Chemicals with … (2020)

  6. No Access

    Article

    Synthesis and Application of Water-Soluble Oxazine Dyes for Detection of PHAs-Producing Bacteria

    Derivatives of oxazine dyes were synthesized on mulitigram scales via efficient synthetic strategies. One practical route was selected to prepare compounds 6, 9 and 10, especially water-soluble compound 6 was obt...

    Qing-Hao Liu, **-Chun Guo, Hong-Yu Lu, Yan-Nan Guo… in Journal of Fluorescence (2018)

  7. No Access

    Article

    Preparation of a Sustained-Release Nebulized Aerosol of R-terbutaline Hydrochloride Liposome and Evaluation of Its Anti-asthmatic Effects via Pulmonary Delivery in Guinea Pigs

    An aerosolized liposome formulation for the pulmonary delivery of an anti-asthmatic medication was developed. Asthma treatment usually requires frequent administration of medication for a sustained bronchodila...

    Qingrui Li, Shuyao Zhan, Qing Liu, Hao Su, ** Dai, Hai Wang… in AAPS PharmSciTech (2018)

  8. No Access

    Article

    Development of a Prolonged-Release Pramipexole Transdermal Patch: In Vitro and In Vivo Evaluation

    The current study aimed to develop a prolonged-release pramipexole (PPX) transdermal patch for the treatment of Parkinson’s disease. Permeation parameters of PPX were investigated using human cadaver skin. Pra...

    Tingting Pu, **aohui Li, Yuming Sun, Xue Ding, Yaqing Pan, Qing Wang in AAPS PharmSciTech (2017)

  9. No Access

    Article

    Antitumor Activity of DMAKO-05, a Novel Shikonin Derivative, and Its Metabolism in Rat Liver Microsome

    The antitumor activity of shikonin derivatives is largely dependent on the generation of superoxide radicals and the alkylation activity of their naphthoquinone moiety. However, our recent study showed that 1,...

    Xu Zhang, Ru-Bing Wang, Wen Zhou, Sui **ao, Qing-Qing Meng… in AAPS PharmSciTech (2015)

  10. No Access

    Article

    A Highly Sensitive Fluorescent Probe for HClO and Its Application in Live Cell Imaging

    A new rhodamine-based probe 1 was designed and synthesized as a new fluorescent molecular probe for HClO in PBS buffer at physiological condition. The free probe 1 almost nonfluorescence, however, a drastic enhan...

    Qing-** Zuo, Zuo-Jun Li, Yong-Hua Hu, Bin Li, Li-Hua Huang… in Journal of Fluorescence (2012)

  11. No Access

    Article

    Study on the Interaction of an Anthracycline Disaccharide with DNA by Spectroscopic Techniques and Molecular Modeling

    This study was designed to examine the interaction of 4′-O-(a-L-Cladinosyl) daunorubicin (DNR–D5), a disaccharide anthracycline with calf thymus deoxyribonucleic acid (ctDNA) by UV/Vis in combination with fluores...

    Yan Lu, Gong-Ke Wang, Juan Lv, Gui-Sheng Zhang, Qing-Feng Liu in Journal of Fluorescence (2011)

  12. No Access

    Article

    Two-photon Absorption Properties of 9,10-Disubstituted 2,6-Bis(p-dihexylaminostyryl)Anthracene Derivatives. Effect of 9,10-Substituents

    A series of 2,6-bis(p-dihexylaminostyryl)anthracence derivatives having phenyl, styryl, and phenylethynyl groups at 9,10-positions (1−4) have been synthesized and their two-photon cross-sections were determined. ...

    Wen Jun Yang, Mun Sik Seo, **ao Qing Wang, Seung-Joon Jeon… in Journal of Fluorescence (2008)