Skip to main content

7 Result(s)

within Qing-**ang Wang Remove this filter Biomedicine Remove this filter Biotechnology Remove this filter Pharmacology/Toxicology Remove this filter

and

  1. No Access

    Article

    The Influence of Various Freezing–thawing Methods of Skin on Drug Permeation and Skin Barrier Function

    The selection of skin is crucial for the in vitro permeation test (IVPT). The purpose of this study was to investigate the influence of different freezing–thawing processes on the barrier function of skin and the...

    **nying Wang, Yuanyuan Zhang, Kaili Liang, Xue Meng, Chunyan Ma… in The AAPS Journal (2024)

  2. No Access

    Article

    Biomimetic Antidote Nanoparticles: a Novel Strategy for Chronic Heavy Metal Poisoning

    Chronic lead poisoning has become a major factor in global public health. Chelation therapy is usually used to manage lead poisoning. Dimercaptosuccinic acid (DMSA) is a widely used heavy metal chelation agent...

    Hao Wang, Qing Yao, Wenquan Zhu, Yang Yang, Chunsheng Gao, Cuiyan Han… in AAPS PharmSciTech (2022)

  3. No Access

    Article

    Enhanced Nuclear Accumulation of Doxorubicin Delivered by pH-Triggered Polydopamine-Shelled Mesoporous Silica for Chemo-Photothermal Therapy

    Adequate delivery of therapeutic agents to their intended molecular targets is crucial in tumor therapy. Versatile drug carriers need to overcome the challenges coming from the systemic circulation, membrane b...

    **aoling Wang, Jiangyue Du, Feng Zhou, Qing Ye, Ying Chen, Dujuan Sun… in AAPS PharmSciTech (2022)

  4. No Access

    Article

    Design of a Long-Acting Rivastigmine Transdermal Delivery System: Based on Computational Simulation

    The purpose of our study was using a computational simulation to develop a long-acting patch of rivastigmine (RVS). A range of patch formulations were screened including pressure sensitive adhesive (PSA), phar...

    Xue Han, **gchuan Liu, **aoyue Hu, Wei Wang, Qing Wang in AAPS PharmSciTech (2022)

  5. No Access

    Article

    Preparation of a Sustained-Release Nebulized Aerosol of R-terbutaline Hydrochloride Liposome and Evaluation of Its Anti-asthmatic Effects via Pulmonary Delivery in Guinea Pigs

    An aerosolized liposome formulation for the pulmonary delivery of an anti-asthmatic medication was developed. Asthma treatment usually requires frequent administration of medication for a sustained bronchodila...

    Qingrui Li, Shuyao Zhan, Qing Liu, Hao Su, ** Dai, Hai Wang… in AAPS PharmSciTech (2018)

  6. No Access

    Article

    Development of a Prolonged-Release Pramipexole Transdermal Patch: In Vitro and In Vivo Evaluation

    The current study aimed to develop a prolonged-release pramipexole (PPX) transdermal patch for the treatment of Parkinson’s disease. Permeation parameters of PPX were investigated using human cadaver skin. Pra...

    Tingting Pu, **aohui Li, Yuming Sun, Xue Ding, Yaqing Pan, Qing Wang in AAPS PharmSciTech (2017)

  7. No Access

    Article

    Antitumor Activity of DMAKO-05, a Novel Shikonin Derivative, and Its Metabolism in Rat Liver Microsome

    The antitumor activity of shikonin derivatives is largely dependent on the generation of superoxide radicals and the alkylation activity of their naphthoquinone moiety. However, our recent study showed that 1,...

    Xu Zhang, Ru-Bing Wang, Wen Zhou, Sui **ao, Qing-Qing Meng… in AAPS PharmSciTech (2015)