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  1. Article

    Open Access

    N-acetylcysteine alleviates post-resuscitation myocardial dysfunction and improves survival outcomes via partly inhibiting NLRP3 inflammasome induced-pyroptosis

    NOD-like receptor 3 (NLRP3) inflammasome is necessary to initiate acute sterile inflammation. Increasing evidence indicates the activation of NLRP3 inflammasome induced pyroptosis is closely related to reactiv...

    Fenglian He, Guanghui Zheng, **gying Hou, Qiaohua Hu, Qin Ling… in Journal of Inflammation (2020)

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  2. Article

    Open Access

    LDK378 improves micro- and macro-circulation via alleviating STING-mediated inflammatory injury in a Sepsis rat model induced by Cecal ligation and puncture

    Sepsis is a systemic inflammatory response syndrome caused by severe infections. LDK378, a second-generation ALK inhibitor, exhibits a potential anti-inflammatory function against sepsis. Micro- and macro-circ...

    Weiwei Ge, Qiaohua Hu, **angshao Fang, Juanhua Liu, **g Xu… in Journal of Inflammation (2019)

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