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  1. No Access

    Article

    Scalable manufacturing methodologies for improving adeno-associated virus-based pharmaprojects

    Adeno-associated virus (AAV) is a promising viral vector and meets most requirements of being a safe biological agent. However, the commercialization of AAV has been hampered due to the limitation of large-sca...

    Zenghui Xu, Chuanyin Shi, Qijun Qian in Chinese Science Bulletin (2014)

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    Article

    Capsid modification of adeno-associated virus and tumor targeting gene therapy

    Targeting is critical for successful tumor gene therapy. The adeno-associated virus (AAV) has aroused wide concern due to its excellent advantages over other viral vectors in gene therapy. AAV has a broad infe...

    ZengHui Xu, **uMei Zhou, WenFang Shi, QiJun Qian in Chinese Science Bulletin (2008)

  3. No Access

    Article

    A novel strategy for cancer treatment: Targeting cancer stem cells

    Cancer stem cell/tumor-initiating cell (CSC/TIC) is a subclass of cancer cells possessing parts of properties of normal stem cell. It has a high capacity of proliferation and plays a pivotal role in tumor recu...

    Jia Liu, LeiNa Ma, YiGang Wang, **nYuan Liu, QiJun Qian in Chinese Science Bulletin (2008)