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  1. Article

    Open Access

    Echinacoside exerts anti-tumor activity via the miR-503-3p/TGF-β1/Smad aixs in liver cancer

    Echinacoside (ECH) is the main active ingredient of Cistanches Herba, which is known to have therapeutic effects on metastatic tumors. However, the effects of ECH on liver cancer are still unclear. This study was...

    Wen Li, **g Zhou, Yajie Zhang, **g Zhang, Xue Li, Qiao Yan… in Cancer Cell International (2021)

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  2. No Access

    Article

    Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

    Mice deficient in BACE1 (beta-site APP cleaving enzyme 1) are healthy, fertile and appear normal in gross anatomy, tissue histology, hematology and clinical chemistry. BACE1−/− mice also hemizygous for an amyloid...

    Yi Luo, Brad Bolon, Steve Kahn, Brian D. Bennett, Safura Babu-Khan… in Nature Neuroscience (2001)

  3. No Access

    Article

    Pharmacological characterization of glial cell line-derived neurotrophic factor (GDNF): implications for GDNF as a therapeutic molecule for treating neurodegenerative diseases

    This review presents a comprehensive survey of the recently described pharmacological activities of glial cell line-derived neurotrophic factor on the central nervous system.

    Paul A. Lapchak, Shoushu Jiao, Paul J. Miller… in Cell and Tissue Research (1996)