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    Article

    Novel Self-assembly Endows Human Serum Albumin Nanoparticles with an Enhanced Antitumor Efficacy

    Protein-based nanomedicine plays an important role in tumor chemotherapy due to their merits in bioavailability, biocompatibility, biodegradability, and low toxicity. In this study, we developed a novel method...

    Dawei Ding, **aolei Tang, **aoli Cao, **hui Wu, Ahu Yuan, Qian Qiao in AAPS PharmSciTech (2014)

  2. Article

    Open Access

    Abnormal dendritic calcium activity and synaptic depotentiation occur early in a mouse model of Alzheimer’s disease

    Alzheimer’s disease (AD) is characterized by amyloid deposition, tangle formation as well as synapse loss. Synaptic abnormalities occur early in the pathogenesis of AD. Identifying early synaptic abnormalities...

    Yang Bai, Miao Li, Yanmei Zhou, Lei Ma, Qian Qiao in Molecular Neurodegeneration (2017)

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    Article

    Transcriptome Sequencing and Screening of Anthocyanin-Related Genes in the Leaves of Acer truncatum Bunge

    Acer truncatum Bunge is generally used as an ornamental tree because of its autumn leaves, although the viewing period is short—approximately 7–15 days. Color improvement of ornamental trees has consistently been...

    FenFen Si, Xue Wang, **ao** Du, JiangYong Wang, JiHan Tao in Biochemical Genetics (2022)

  4. Article

    Open Access

    RBM10 C761Y mutation induced oncogenic ASPM isoforms and regulated β-catenin signaling in cholangiocarcinoma

    Cholangiocarcinoma (CCA) comprises a heterogeneous group of biliary tract cancer. Our previous CCA mutation pattern study focused on genes in the post-transcription modification process, among which the altern...

    Jiang Chang, Yaodong Zhang, Tao Zhou in Journal of Experimental & Clinical Cancer … (2024)