629 Result(s)
within
Qian** Li
Life Sciences
-
Article
Open AccessMulticenter proteome-wide Mendelian randomization study identifies causal plasma proteins in melanoma and non-melanoma skin cancers
This study addresses the diagnostic and therapeutic challenges in malignant melanoma (MM) and non-melanoma skin cancers (NMSC). We aim to identify circulating proteins causally linked to MM and NMSC traits usi...
-
Article
Open AccessGenetic Dissection of Major Rice QTLs for Strong Culms and Fine Map** of qWS5 for Breeding Application in Transplanted System
Rice is one of the major staples that feeds about one half of the global populations, and it is important to identify the genetic loci for the traits related to yield improvement. Lodging will cause severe yie...
-
Article
Open AccessEndosomal protein DENND10/FAM45A integrates extracellular vesicle release with cancer cell migration
Mounting evidence shows that tumor-derived extracellular vesicles (EVs) are critical constituents in the tumor microenvironment. The composition and function of EVs often change during cancer progression. Howe...
-
Article
Open AccessGenome-wide identification and analysis of monocot-specific chimeric jacalins (MCJ) genes in Maize (Zea mays L.)
The monocot chimeric jacalins (MCJ) proteins, which contain a jacalin-related lectin (JRL) domain and a dirigent domain (DIR), are specific to Poaceae. MCJ gene family is reported to play an important role in ...
-
Article
Open AccessAcceleration of bone repairation by BMSCs overexpressing NGF combined with NSA and allograft bone scaffolds
Repairation of bone defects remains a major clinical problem. Constructing bone tissue engineering containing growth factors, stem cells, and material scaffolds to repair bone defects has recently become a hot...
-
Article
Overcoming genotypic dependency and bypassing immature embryos in wheat transformation by using morphogenic regulators
-
Article
The Association Between the Levels of Oxidative Stress Indicators (MDA, SOD, and GSH) in Seminal Plasma and the Risk of Idiopathic Oligo-asthenotera-tozoospermia: Does Cu or Se Level Alter the Association?
Epidemiological studies on the associations between the levels of oxidative stress (OS) indicators (MDA, SOD, and GSH) in seminal plasma and the risk of idiopathic oligo-asthenotera-tozoospermia (OAT) are stil...
-
Article
Plastome structure, phylogeny and evolution of plastid genes in Reevesia (Helicteroideae, Malvaceae)
Reevesia is an eastern Asian-eastern North American disjunction genus in the family Malvaceae s.l. and comprises approximately 25 species. The relationships within the genus are not well understood. Here, 15 plas...
-
Article
Open AccessA pan-KRAS degrader for the treatment of KRAS-mutant cancers
KRAS mutations are highly prevalent in a wide range of lethal cancers, and these mutant forms of KRAS play a crucial role in driving cancer progression and conferring resistance to treatment. While there have bee...
-
Article
Desktop-Stereolithography 3D Printing of a Decellularized Extracellular Matrix/Mesenchymal Stem Cell Exosome Bioink for Vaginal Reconstruction
3D-printing is widely used in regenerative medicine and is expected to achieve vaginal morphological restoration and true functional reconstruction. Mesenchymal stem cells-derived exosomes (MSCs-Exos) were app...
-
Article
A modified method for isolating sinoatrial node myocytes from adult mice
Sinoatrial node (SAN) is the pacemaker of the heart in charge of initiating spontaneous electronical activity and controlling heart rate. Myocytes from SAN can generate spontaneous rhythmic action potentials, ...
-
Article
Optimizing Nitrogen Fertilization Managements Under Mechanical Deep Placement for Raising Rice Grain Yield
It is not known whether both reducing tiller-fertilizer and increasing panicle-fertilizer can significantly increase grain yield under mechanical deep placement. The two-year field experiment was conducted to ...
-
Article
Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms
Smc5/6 is a member of the eukaryotic structural maintenance of chromosomes (SMC) family of complexes with important roles in genome maintenance and viral restriction. However, limited structural understanding ...
-
Article
Open AccessThe complete mitochondrial genomes of five critical phytopathogenic Bipolaris species: features, evolution, and phylogeny
In the present study, three mitogenomes from the Bipolaris genus (Bipolaris maydis, B. zeicola, and B. oryzae) were assembled and compared with the other two reported Bipolaris mitogenomes (B. oryzae and B. sorok...
-
Article
Association Between Serum Zinc and Non-Alcoholic Fatty Liver Disease and Advanced Liver Fibrosis: NHANES 2011–2016
Limited and inconclusive evidence exists regarding the correlation between serum zinc levels and non-alcoholic fatty liver disease (NAFLD) and advanced fibrosis. The objective of this cross-sectional study was...
-
Article
Open AccessARID1A loss promotes RNA editing of CDK13 in an ADAR1-dependent manner
ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, is thought to play a significant role both in tumor suppression and tumor initiation, which is highly dependent upon context. Previous studies hav...
-
Article
Identification of a QTL for Setaria italica bristle length using QTL-seq
Long bristles facilitate seed dispersal and protect seeds from herbivores. Early domesticated Setaria italica cultivars had long bristles, but most of the modern cultivars have short bristles. Little is known abo...
-
Article
Non-destructive estimation of leaf moisture content of Epipremnum aureum based on electrical impedance spectroscopy
Electrical impedance spectroscopy (EIS) is a technique used for detection of leaf moisture content (LMC). Generally, EIS is inconvenient and destructive. This paper proposed a non-destructive method for predic...
-
Article
Interactive Effects of Drip Irrigation and Nitrogen Fertilization on Wheat and Maize Yield: A Meta-analysis
Population growth and climate change are pushing the need for sustainable food production and reduced water usage in agriculture due to limited water resources. Irrigation and fertilization have been proposed ...
-
Article
Treatment of Syringomyelia Characterized by Focal Dilatation of the Central Canal Using Mesenchymal Stem Cells and Neural Stem Cells
Syringomyelia is a progressive chronic disease that leads to nerve pain, sensory dissociation, and dyskinesia. Symptoms often do not improve after surgery. Stem cells have been widely explored for the treatmen...
