1,821 Result(s)

Article

CT Angiography Radiomics Combining Traditional Risk Factors to Predict Brain Arteriovenous Malformation Rupture: a Machine Learning, Multicenter Study

This study aimed to develop a machine learning model for predicting brain arteriovenous malformation (bAVM) rupture using a combination of traditional risk factors and radiomics features. This multicenter retr...

Shaosen Zhang, Junjie Wang, Shengjun Sun, Qian Zhang… in Translational Stroke Research (2024)

Article

Associations of Rheumatoid Factor, Rheumatoid Arthritis, and Interleukin-6 Inhibitor with the Prognosis of Ischemic Stroke: a Prospective Multicenter Cohort Study and Mendelian Randomization Analysis

Rheumatoid factor (RF), an established diagnostic biomarker for rheumatoid arthritis (RA), is associated with cardiovascular diseases, but its impact on clinical outcomes of ischemic stroke remains unclear. We...

Yiming Jia, Kaixin Zhang, Mengyao Shi, Daoxia Guo… in Translational Stroke Research (2024)

Article

Imaging features of pediatric meningiomas: emphasis on unusual locations

This article aims to analyze pediatric meningioma’s imaging characteristics, especially those in unusual locations.

Qingyang Shi, Jiajie Tian, Tingting Zhou, Na Tan, Tijiang Zhang… in Child's Nervous System (2024)

Article

Self-expanding intracranial drug-eluting stent system in patients with symptomatic intracranial atherosclerotic stenosis: initial experience and midterm angiographic follow-up

Symptomatic intracranial atherosclerotic stenosis (ICAS) is a major cause of ischemic stroke worldwide. In patients undergoing endovascular treatment for ICAS, in-stent restenosis (ISR) is associated with isch...

Feifan Zhang, **biao Yao, Pei Wu, Qiaowei Wu, Chunxu Li, **shuo Yang… in Neuroradiology (2024)

Article

Neurobiology of Obsessive–Compulsive Disorder from Genes to Circuits: Insights from Animal Models

Obsessive-compulsive disorder (OCD) is a chronic, severe psychiatric disorder that has been ranked by the World Health Organization as one of the leading causes of illness-related disability, and first-line in...

Ying-Dan Zhang, Dong-Dong Shi, Zhen Wang in Neuroscience Bulletin (2024)

Article

Evaluation of AAV Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy

Nosebleeds and intracranial hemorrhage from brain arteriovenous malformations (bAVMs) are among the most devastating symptoms of patients with hereditary hemorrhagic telangiectasis (HHT). All available managem...

Alka Yadav, Rich Liang, Kelly Press, Annika Schmidt… in Translational Stroke Research (2024)

Article

Navβ2 Intracellular Fragments Contribute to Aβ1-42-Induced Cognitive Impairment and Synaptic Deficit Through Transcriptional Suppression of BDNF

A pathological hallmark of Alzheimer’s disease (AD) is the region-specific accumulation of the amyloid-beta protein (Aβ), which triggers aberrant neuronal excitability, synaptic impairment, and progressive cog...

Min-Nan Lu, Dan Wang, Chen-Jun Ye, Guo-Ji Yan, **g-Feng Song… in Molecular Neurobiology (2024)

Article

Huanglian Wendan Decoction Improves Insomnia in Rats by Regulating BDNF/TrkB Signaling Pathway Through Gut Microbiota-Mediated SCFAs and Affecting Microglia Polarization

Insomnia is a typical type of sleep disorder. Huanglian Wendan Decoction (HWD) is a traditional Chinese medicine (TCM) with the effects of regulating Qi, drying dampness and resolving phlegm, calming the mind, an...

Min Shi, Jie Yang, Ying Liu, Huan Zhao, Man Li, Dongdong Yang… in Molecular Neurobiology (2024)

Article

Bispecific BCMA/CD19 targeted CAR-T cell therapy forces sustained disappearance of symptoms and anti-acetylcholine receptor antibodies in refractory myasthenia gravis: a case report

Yong Zhang, Dan Liu, Zhouao Zhang, **aoyu Huang, Jiang Cao… in Journal of Neurology (2024)

Article

Effect and Mechanism of LIN28 on Ferroptosis in Mg²⁺-free Rat Hippocampal Neuron Model of Epilepsy

Studies have demonstrated that LIN28 is expressed in the CNS and may exert protective effects on neurons. However, it remains unknown whether LIN28 regulates ferroptosis in the context of epilepsy. In this stu...

**aoke Wu, Mengmeng Shi, Yuan Chen, Yajun Lian, Shaokuan Fang… in Neurochemical Research (2024)

Article

Autistic and Non-autistic Children’s Pain Perception is Modulated by Their First-Hand Pain Sensitivity and Theory of Mind

The current study examined whether autistic children’s perception of others’ pain could be modulated by their first-hand pain sensitivity and theory of mind (ToM). We measured the first-hand pain sensitivity, ...

Tianbi Li, Qianhan **ong, Ruoxi Shi, Li Yi in Research on Child and Adolescent Psychopat… (2024)

Article

A Synthetic Steroid 5α-Androst-3β, 5, 6β-triol Alleviates Radiation-Induced Brain Injury in Mice via Inhibiting GBP5/NF-κB/NLRP3 Signal Axis

Radiotherapy for head and neck tumors can lead to a severe complication known as radiation-induced brain injury (RIBI). However, the underlying mechanism of RIBI development remains unclear, and limited preven...

Ke Zhong, Kejia Liu, Yu Song, Sitai Chen, **a Hu, Ruiqi Xue… in Molecular Neurobiology (2024)

Article

The Protective Mechanism of TFAM on Mitochondrial DNA and its Role in Neurodegenerative Diseases

Mitochondrial transcription factor A (TFAM) is a mitochondrial protein encoded by nuclear genes and transported from the cytoplasm to the mitochondria. TFAM is essential for the maintenance, expression, and de...

Ying Song, Wenjun Wang, Beibei Wang, Qiwen Shi in Molecular Neurobiology (2024)

Article

Correlation between severe attacks and serum aquaporin-4 antibody titer in neuromyelitis optica spectrum disorder

Aquaporin 4-immunoglobulin G (AQP4-IgG) specifically targets aquaporin 4 in approximately 80% of Neuromyelitis Optica Spectrum Disorder (NMOSD) cases. NMOSD is presently categorized as anti-AQP4-antibody (Ab) ...

Rui Wang, Dongren Sun, **aofei Wang, Ziyan Shi, Lingyao Kong… in Journal of Neurology (2024)

Article

The Role of Iron Metabolism in Sepsis-associated Encephalopathy: a Potential Target

Sepsis-associated encephalopathy (SAE) is an acute cerebral dysfunction secondary to infection, and the severity can range from mild delirium to deep coma. Disorders of iron metabolism have been proven to play...

Yinuo Liu, Shengnan Hu, Bowen Shi, Bodong Yu, Wei Luo… in Molecular Neurobiology (2024)

Article

SIRT3-Mediated Deacetylation of SDHA Rescues Mitochondrial Bioenergetics Contributing to Neuroprotection in Rotenone-Induced PD Models

Mitochondrial dysfunction is critically involved in the degeneration of dopamine (DA) neurons in the substantia nigra, a common pathological feature of Parkinson’s disease (PD). Previous studies have demonstra...

Yanhua Shen, Xueting Wang, Nan Nan, **aolong Fu, Ru Zeng… in Molecular Neurobiology (2024)