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Article
Mammary duct luminal epithelium controls adipocyte thermogenic programme
Sympathetic activation during cold exposure increases adipocyte thermogenesis via the expression of mitochondrial protein uncoupling protein 1 (UCP1)1. The propensity of adipocytes to express UCP1 is under a crit...
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Article
Open AccessNOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice
We recently showed that NOTUM, a liver-secreted Wnt inhibitor, can acutely promote browning of white adipose. We now report studies of chronic overexpression of NOTUM in liver indicating that it protects again...
