4 Result(s)
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Prabhakar S. Andhey
Biomedicine, general
Infectious Diseases
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Article
Publisher Correction: Human early-onset dementia caused by DAP12 deficiency reveals a unique signature of dysregulated microglia
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Article
Human early-onset dementia caused by DAP12 deficiency reveals a unique signature of dysregulated microglia
The TREM2–DAP12 receptor complex sustains microglia functions. Heterozygous hypofunctional TREM2 variants impair microglia, accelerating late-onset Alzheimer’s disease. Homozygous inactivating variants of TREM2 o...
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Article
Author Correction: Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
Glia have been implicated in Alzheimer’s disease (AD) pathogenesis. Variants of the microglia receptor triggering receptor expressed on myeloid cells 2 (TREM2) increase AD risk, and activation of disease-assoc...
