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Target Discovery for Precision Medicine Using High-Throughput Genome Engineering
Over the past few years, programmable RNA-guided nucleases such as the CRISPR/Cas9 system have ushered in a new era of precision genome editing in diverse model systems and in human cells. Functional screens u...
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Article
Open AccessA comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome
H37Rv is the most widely used Mycobacterium tuberculosis strain, and its genome is globally used as the M. tuberculosis reference sequence. Here, we present Bact-Builder, a pipeline that uses consensus building t...
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Article
Open AccessAuthor Correction: A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome