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  1. Article

    Open Access

    DEPDC5 protects CD8+ T cells from ferroptosis by limiting mTORC1-mediated purine catabolism

    Peripheral CD8+ T cell number is tightly controlled but the precise molecular mechanism regulating this process is still not fully understood. In this study, we found that epilepsy patients with loss of function ...

    Song Li, **nxing Ouyang, Hongxiang Sun, **gsi **, Yao Chen, Liang Li… in Cell Discovery (2024)

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  2. No Access

    Article

    SUnSET, a nonradioactive method to monitor protein synthesis

    As an alternative to the use of radioactively labeled amino acids, incorporation of puromycin into proteins allows evaluation of translation in heterogenous cell populations by flow cytometry analysis after st...

    Enrico K Schmidt, Giovanna Clavarino, Maurizio Ceppi, Philippe Pierre in Nature Methods (2009)

  3. Article

    Open Access

    Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

    Dendritic cells (DCs) are a complex group of cells that play a critical role in vertebrate immunity. Lymph-node resident DCs (LN-DCs) are subdivided into conventional DC (cDC) subsets (CD11b and CD8α in mouse;...

    Scott H Robbins, Thierry Walzer, Doulaye Dembélé, Christelle Thibault… in Genome Biology (2008)

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