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  1. Article

    Open Access

    Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization

    Sterol regulatory element-binding protein (SREBP) transcription factors are master regulators of cellular lipid homeostasis in mammals and oxygen-responsive regulators of hypoxic adaptation in fungi. SREBP C-t...

    **n Gong, Hongwu Qian, Wei Shao, **gxian Li, Jian** Wu, Jun-Jie Liu… in Cell Research (2016)

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  2. Article

    Open Access

    Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition

    The sterol regulatory element-binding protein (SREBP) and SREBP cleavage-activating protein (SCAP) are central players in the SREBP pathway, which control the cellular lipid homeostasis. SCAP binds to SREBP th...

    **n Gong, **gxian Li, Wei Shao, Jian** Wu, Hongwu Qian, Ruobing Ren… in Cell Research (2015)

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