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  1. Article

    Open Access

    Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia/reperfusion injury via suppressing GPX4-mediated ferroptosis

    Ischemia/reperfusion (I/R)-induced liver injury with severe cell death is a major complication of liver transplantation. Transmembrane member 16A (TMEM16A), a component of hepatocyte Ca2+-activated chloride chann...

    Jiawei Guo, Zihao Song, Jie Yu, Chengyi Li, Chenchen **, Wei Duan… in Cell Death & Disease (2022)

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  2. Article

    Open Access

    Mesenchymal stem cell-derived conditioned medium protects vascular grafts of brain-dead rats against in vitro ischemia/reperfusion injury

    Brain death (BD) has been suggested to induce coronary endothelial dysfunction. Ischemia/reperfusion (IR) injury during heart transplantation may lead to further damage of the endothelium. Previous studies hav...

    Sevil Korkmaz-Icöz, Pengyu Zhou, Yuxing Guo… in Stem Cell Research & Therapy (2021)

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  3. Article

    Open Access

    Donor heart preservation with hypoxic-conditioned medium-derived from bone marrow mesenchymal stem cells improves cardiac function in a heart transplantation model

    In heart transplantation, donor hearts inevitably suffer from ischemia/reperfusion (I/R) injury, which leads to primary graft dysfunction and affects patients’ survival rate. Bone marrow mesenchymal stem cells...

    Pengyu Zhou, Hao Liu, **mao Liu, **ao Ling, Zezhou **ao… in Stem Cell Research & Therapy (2021)

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  4. Article

    Open Access

    The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3

    Yersinia pestis uses type III effector proteins to target eukaryotic signaling systems. The Yersinia outer protein (Yop) M effector from the Y . pestis strain is a critical virulence determinant; however, its rol...

    Congwen Wei, Ying Wang, Zongmin Du, Kai Guan, Ye Cao, Huiying Yang… in Cell Death & Disease (2016)

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