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Article
Open AccesslncRNA-SOX2OT promotes hepatocellular carcinoma invasion and metastasis through miR-122-5p-mediated activation of PKM2
Tumor cells primarily utilize aerobic glycolysis for energy production, a phenomenon known as the Warburg effect, but the involvement of Warburg effect in liver cancer cell metastasis is not well understood. I...
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Article
Haplotype-Based Case-Control Study of the Association between the Guanylate Cyclase Activator 2B (GUCA2B, Uroguanylin) Gene and Essential Hypertension
Uroguanylin (gene name: guanylate cyclase activator 2B, GUCA2B) is a peptide regulator of intestinal salt and water transport. It has been reported that the uroguanylin knockout mouse exhibits elevated blood p...
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Article
Common Single Nucleotide Polymorphisms in Japanese Patients with Essential Hypertension: Aldehyde Dehydrogenase 2 Gene as a Risk Factor Independent of Alcohol Consumption
Essential hypertension (EH) is a multifactorial disorder determined by the interaction of environmental and genetic factors. EH patients' responses to these factors may vary, depending on differences in their ...