4 Result(s)
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Pasquale D′Acunzo
Cell Biology
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Article
Open AccessSex Differentially Alters Secretion of Brain Extracellular Vesicles During Aging: A Potential Mechanism for Maintaining Brain Homeostasis
Extracellular vesicles (EVs) in the brain play a role in neuronal homeostasis by removing intracellular material and regulating cell-to-cell communication. Given that sex and aging differentially modulate brai...
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Article
Open AccessCocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner
In multiple neurodevelopmental and neurodegenerative disorders, endosomal changes correlate with changes in exosomes. We examined this linkage in the brain of mice that received cocaine injections for two week...
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Article
Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy
The role of mitophagy, a process that allows the removal of damaged mitochondria from cells, remains unknown in multiple sclerosis (MS), a disease that is found associated with dysfunctional mitochondria. Here...
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Article
Open Accessc-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability
c-FLIP (cellular FLICE-like inhibitory protein) protein is mostly known as an apoptosis modulator. However, increasing data underline that c-FLIP plays multiple roles in cellular homoeostasis, influencing diff...
