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  1. No Access

    Article

    Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues

    Extracellular vesicles (EVs) are nanoscale vesicles secreted into the extracellular space by all cell types, including neurons and astrocytes in the brain. EVs play pivotal roles in physiological and pathophys...

    Pasquale D’Acunzo, Yohan Kim, Jonathan M. Ungania, Rocío Pérez-González… in Nature Protocols (2022)

  2. No Access

    Article

    Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy

    The role of mitophagy, a process that allows the removal of damaged mitochondria from cells, remains unknown in multiple sclerosis (MS), a disease that is found associated with dysfunctional mitochondria. Here...

    Anthea Di Rita, Daniela F. Angelini, Teresa Maiorino… in Cell Death & Differentiation (2021)

  3. Article

    Open Access

    c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability

    c-FLIP (cellular FLICE-like inhibitory protein) protein is mostly known as an apoptosis modulator. However, increasing data underline that c-FLIP plays multiple roles in cellular homoeostasis, influencing diff...

    Luana Tomaipitinca, Simonetta Petrungaro, Pasquale D’Acunzo… in Cell Death & Disease (2021)

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