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  1. No Access

    Article

    Can we predict pathology without surgery? Weighing the added value of multiparametric MRI and whole prostate radiomics in integrative machine learning models

    To test the ability of high-performance machine learning (ML) models employing clinical, radiological, and radiomic variables to improve non-invasive prediction of the pathological status of prostate cancer (P...

    Giulia Marvaso, Lars Johannes Isaksson, Mattia Zaffaroni in European Radiology (2024)

  2. Article

    Open Access

    Comparison of automated segmentation techniques for magnetic resonance images of the prostate

    Contouring of anatomical regions is a crucial step in the medical workflow and is both time-consuming and prone to intra- and inter-observer variability. This study compares different strategies for automatic ...

    Lars Johannes Isaksson, Matteo Pepa, Paul Summers, Mattia Zaffaroni in BMC Medical Imaging (2023)

  3. Article

    Open Access

    Quality assurance for automatically generated contours with additional deep learning

    Deploying an automatic segmentation model in practice should require rigorous quality assurance (QA) and continuous monitoring of the model’s use and performance, particularly in high-stakes scenarios such as ...

    Lars Johannes Isaksson, Paul Summers, Abhir Bhalerao, Sara Gandini in Insights into Imaging (2022)

  4. Article

    Open Access

    Whole-body magnetic resonance imaging (WB-MRI) for cancer screening: recommendations for use

    Whole-body magnetic resonance imaging (WB-MRI) is currently recommended for cancer screening in adult and paediatric subjects with cancer predisposition syndromes, representing a substantial aid for prolonging...

    Giuseppe Petralia, Fabio Zugni, Paul E. Summers, Alberto Colombo in La radiologia medica (2021)

  5. No Access

    Article

    MRI-based radiomics signature for localized prostate cancer: a new clinical tool for cancer aggressiveness prediction? Sub-study of prospective phase II trial on ultra-hypofractionated radiotherapy (AIRC IG-13218)

    Radiomic involves testing the associations of a large number of quantitative imaging features with clinical characteristics. Our aim was to extract a radiomic signature from axial T2-weighted (T2-W) magnetic r...

    Simone Giovanni Gugliandolo, Matteo Pepa, Lars Johannes Isaksson in European Radiology (2021)

  6. Article

    Open Access

    Whole-body magnetic resonance imaging (WB-MRI) reporting with the METastasis Reporting and Data System for Prostate Cancer (MET-RADS-P): inter-observer agreement between readers of different expertise levels

    The METastasis Reporting and Data System for Prostate Cancer (MET-RADS-P) guidelines are designed to enable reproducible assessment in detecting and quantifying metastatic disease response using whole-body mag...

    Paola Pricolo, Eleonora Ancona, Paul Summers, Jorge Abreu-Gomez in Cancer Imaging (2020)

  7. No Access

    Article

    Phase II prospective trial “Give Me Five” short-term high precision radiotherapy for early prostate cancer with simultaneous boost to the dominant intraprostatic lesion: the impact of toxicity on quality of life (AIRC IG-13218)

    As part of the AIRC IG-13218 (NCT01913717), we analyzed data from patients with low- and intermediate-risk prostate cancer treated with extreme hypofractionated radiotherapy (RT) and simultaneous boost to the ...

    Giulia Marvaso, Simone Giovanni Gugliandolo, Federica Bellerba in Medical Oncology (2020)

  8. Article

    Open Access

    Low PI-RADS assessment category excludes extraprostatic extension (≥pT3a) of prostate cancer: a histology-validated study including 301 operated patients

    To evaluate whether low PI-RADS v2 assessment categories are effective at excluding extraprostatic extension (EPE) of prostate cancer (≥pT3a PCa).

    Sarah Alessi, Paola Pricolo, Paul Summers, Marco Femia in European Radiology (2019)

  9. No Access

    Article

    Whole-body magnetic resonance imaging (WB-MRI) in oncology: recommendations and key uses

    The past decade has witnessed a growing role and increasing use of whole-body magnetic resonance imaging (WB-MRI). Driving these successes are developments in both hardware and software that have reduced overa...

    Giuseppe Petralia, Anwar R. Padhani, Paola Pricolo, Fabio Zugni in La radiologia medica (2019)

  10. Article

    Open Access

    Linear asymptomatic pneumatosis as an unexpected finding of computed tomography colonography: a case report

    We discuss asymptomatic colonic pneumatosis, an unexpected finding of computed tomography colonography that we must see as distinct from perforation. Among the papers detailing complications with computed tomo...

    Nicola Flor, Paola Pricolo, Antonio Rovere in Journal of Medical Case Reports (2013)