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Article
Open AccessSafety and efficacy of P2Et extract from Caesalpinia spinosa in breast cancer patients: study protocol for a randomized double blind phase II clinical trial (CS003-BC)
Chemotherapy in breast cancer is effective but can generate significant toxicity and lead to tumor resistance. Joint treatment with standardized plant extracts can be an alternative to improve the response and...
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Article
Open AccessExploring the safety and efficacy of phytomedicine Petiveria alliacea extract (Esperanza) in patients with metastatic gastrointestinal tumors and acute leukemias: study protocol for a phase Ib/randomized double blind phase II trial (PA001)
The energy metabolism of drug-resistant tumor cells can provide a survival advantage during therapy, and treatment itself may influence metabolic reprogramming. Petiveria alliacea (Traditional name: Anamu) could ...
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Article
Open AccessGlycemic status and health-related quality of life (HRQOL) in populations at risk of diabetes in two Latin American cities
To estimate the health-related quality of life (HRQOL) according to glycemic status, and its relationship with sociodemographic and clinical factors in a population at risk of develo** type 2 diabetes (T2D).
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Article
Open AccessHealth-related quality of life (HRQoL) in a population at risk of type 2 diabetes: a cross-sectional study in two Latin American cities
The purpose of this study was to describe the health-related quality of life (HRQoL) characteristics in a population at risk of develo** type 2 diabetes in Barranquilla and Bogotá, Colombia.
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Article
Open AccessScreening, prevalence, treatment and control of kidney disease in patients with type 1 and type 2 diabetes in low-to-middle-income countries (2005–2017): the International Diabetes Management Practices Study (IDMPS)
Diabetes is the leading cause of kidney disease worldwide. There is limited information on screening, treatment and control of kidney disease in patients with diabetes in low-to-middle-income countries (LMICs).
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Article
Open AccessOne in Seven Insulin-Treated Patients in Develo** Countries Reported Poor Persistence with Insulin Therapy: Real World Evidence from the Cross-Sectional International Diabetes Management Practices Study (IDMPS)
Although poor adherence to insulin is widely recognised, periodic discontinuation of insulin may cause more severe hyperglycaemia than poor adherence. We assessed persistence with insulin therapy in patients w...
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Article
Open AccessGlycemic Control and Prevention of Diabetic Complications in Low- and Middle-Income Countries: An Expert Opinion
Trends on glycemic control and diabetes complications are known for high-income countries, but comprehensive data from low- and middle-income countries (LMIC) are lacking.
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Article
Correction to: Persistent poor glycaemic control in individuals with type 2 diabetes in develo** countries: 12 years of real-world evidence of the International Diabetes Management Practices Study (IDMPS)
Unfortunately, the standard deviations for ‘last HbA1c measurement’ in mmol/mol were miscalculated in Table 1 of this paper.
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Article
Open AccessPersistent poor glycaemic control in individuals with type 2 diabetes in develo** countries: 12 years of real-world evidence of the International Diabetes Management Practices Study (IDMPS)
We evaluated the secular trend of glycaemic control in individuals with type 2 diabetes in develo** countries, where data are limited.
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Article
Open AccessEfficacy and Safety of iGlarLixi, Fixed-Ratio Combination of Insulin Glargine and Lixisenatide, Compared with Basal-Bolus Regimen in Patients with Type 2 Diabetes: Propensity Score Matched Analysis
Basal-bolus (BB) regimens are generally used to intensify basal insulin therapy in patients with type 2 diabetes (T2D) not meeting glycemic targets. However, drawbacks include multiple injection burden and ris...
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Reference Work Entry In depth
Obesity in Latin America
Obesity in Latin America has become a serious health problem. The highest prevalence in adults is now seen in Mexico (more than 30 %), and in children, it is seen in girls in Uruguay (more than 15 %). Obesity ...
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Article
Open AccessInadequate glucose control in type 2 diabetes is associated with impaired lung function and systemic inflammation: a cross-sectional study
Inadequate glucose control may be simultaneously associated with inflammation and decreased lung function in type 2 diabetes. We evaluated if lung function is worse in patients with inadequate glucose control,...