Skip to main content

6 Result(s)

within PT Daniel Remove this filter Medicine/Public Health, general Remove this filter Oncology Remove this filter

and

  1. Article

    Open Access

    Assessment of free light chains in the cerebrospinal fluid of patients with lymphomatous meningitis – a pilot study

    Lymphomatous meningitis (LM) represents a severe complication of malignant lymphomas. While clinical suspicion is raised by symptoms ranging from mild disturbances of sensation to severe pain or impaired consc...

    B Hildebrandt, C Müller, A Pezzutto, PT Daniel, B Dörken, C Scholz in BMC Cancer (2007)

    Download PDF (213 KB) View Article

  2. No Access

    Article

    Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

    In B-CLL, non-proliferating B cells accumulate due to defective apoptosis. Cytotoxic therapies trigger apoptosis and deregulation of apoptotic pathways contributes to chemoresistance. Loss of the apoptosis-pro...

    AG Bosanquet, I Sturm, T Wieder, F Essmann, MI Bosanquet, DJ Head, B Dörken… in Leukemia (2002)

  3. No Access

    Article

    Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblasts

    The stilbene phytochemicals resveratrol and piceatannol have been reported to possess substantial antitumorigenic and antileukemic activities, respectively. Although recent experimental data revealed the proap...

    T Wieder, A Prokop, B Bagci, F Essmann, D Bernicke, K Schulze-Osthoff, B Dörken… in Leukemia (2001)

  4. No Access

    Article

    The kiss of death: promises and failures of death receptors and ligands in cancer therapy

    Death receptors and their ligands exert important regulatory functions in the maintenance of tissue homeostasis and the physiological regulation of programmed cell death. Currently, six different death recepto...

    PT Daniel, T Wieder, I Sturm, K Schulze-Osthoff in Leukemia (2001)

  5. No Access

    Article

    Dissecting the pathways to death

    This report summarizes recent findings in the field of basic and translational apoptosis research which were presented at the 1st Conference on ‘Mechanisms of Cell Death and Disease: Advances in Therapeutic In...

    PT Daniel in Leukemia (2000)

  6. No Access

    Article

    Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

    Dysfunction of the p53/Bax/caspase-3 apoptosis signaling pathway has been shown to play a role in tumorigenesis and tumor progression, ie the development of acquired drug resistance. Low expression of the apop...

    A Prokop, T Wieder, I Sturm, F Eβmann, K Seeger, C Wuchter, W-D Ludwig, G Henze… in Leukemia (2000)