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Article

Impact of primary resistance to front-line targeted therapy in metastatic renal cell carcinoma on subsequent immune-checkpoint-inhibition

Synergistic effects have been discussed for tyrosine kinase (TKI) and immune checkpoint inhibitors (ICI). Primary resistance to TKI might disturb subsequent ICI effectiveness. The objective was to investigate,...

J. H. Börner, S. Neuberger, E. Juengel, S. Ziewers, R. Dotzauer… in Discover Oncology (2023)