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Chapter and Conference Paper
Messung der analgetischen Wirkung mit subjektiven und objektiven Parametern
Zur Beurteilung der analgetischen Wirkung von schwachen Schmerzmitteln wurden in einer Versuchsreihe mit 14 Probanden subjektive und objektive Parameter zur Schmerzmessung verfolgt und miteinander verglichen.
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Chapter and Conference Paper
Pneumologie
Überschießende Bronchokonstriktion auf geringe Reize ist das bekannteste, aber keineswegs einzige Charakteristikum eines hyperreagiblen Bronchialsystems. Da u. a. eine Fehlregulation des autonomen Nervensystem...
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Article
Identification of glucocorticoid receptors in normal and neoplastic adult human lung
A dexamethasone-binding protein was detected in cytosol of five normal and three neoplastic lung tissue samples. The apparent dissociation constant of the dexamethasone protein complex ranged from 5.8 to 21 nM (1...
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Article
Pharmacokinetics of triamcinolone acetonide and its phosphate ester
Triamcinolone acetonide in the form of its phosphate ester was given intravenously in two different doses (10 mg/kg and 80 mg). Plasma levels of the ester and triamcinolone acetonide were measured and pharmaco...
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Article
Affinities of glucocorticoids for glucocorticoid receptors in the human lung
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Article
Dose-dependent pharmacokinetics of metabolites of dipyrone in saliva
Metabolites of dipyrone have been determined in the saliva of 18 volunteers following the oral intake of 0.5 g, 1.0 g, 1.5 g, 2.0 g and 2.5 g dipyrone. High concentrations were measured for N-methyl-aminoantip...
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Chapter and Conference Paper
Pharmacokinetic Aspects of Intra-articular Administration of Glucocorticoids
Für die intraartikuläre Glukokortikoidtherapie stehen zahlreiche Kristallsuspensionen zur Verfügung. Die wichtigsten Vertreter sind Triamcinolondiacetat, Triamcinolonacetonid, Triamcinolonhexacetonid, Betameth...
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Article
Improvement of erectile function with Prelox: a randomized, double-blind, placebo-controlled, crossover trial
In a randomly allocated, double-blind, placebo-controlled, crossover design, 50 patients with mild to moderate erectile dysfunction (ED) were treated for 1 month with placebo or a combination of L-arginine aspart...