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  1. Article

    Open Access

    Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK

    Mantle cell lymphoma (MCL) is a currently incurable B-cell malignancy. Lenalidomide (Len) has been demonstrated to be one of the most efficient new treatment options. Because Len and 1α,25-dihydroxyvitamin (VD...

    C Brosseau, C Dousset, C Touzeau, S Maïga, P Moreau, M Amiot… in Cell Death & Disease (2014)

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  2. No Access

    Article

    Increase in HLA-G1 proteolytic shedding by tumor cells: a regulatory pathway controlled by NF-κB inducers

    HLA-G is expressed by tumors, in which it contributes to the evasion of immunosurveillance. NF-κB appears to be a candidate for regulating HLA-G expression, since it is considered to be a hallmark of cancer. W...

    I. Zidi, C. Guillard, C. Marcou… in Cellular and Molecular Life Sciences CMLS (2006)

  3. No Access

    Article

    HLA-G protein processing and transport to the cell surface

    Data are presented on the intracellular trafficking of HLA-G protein, taking the unique features of this non-classical molecule into consideration: the existence of seven isoforms resulting from alternative s...

    P. Moreau, P. Rousseau, N. Rouas-Freiss… in Cellular and Molecular Life Sciences CMLS (2002)

  4. Article

    Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas

    FasL and TRAIL are apoptotic ligands of the TNF-like cytokines family, acting via activation of the transmembrane death domain containing receptors Fas for FasL, and DR4 or DR5 for TRAIL. A glycosylphosphatidy...

    P Legembre, P Moreau, S Daburon, J-F Moreau, J-L Taupin in Cell Death & Differentiation (2002)

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  5. No Access

    Article

    Altered HLA-G transcription in pre-eclampsia is associated with allele specific inheritance: possible role of the HLA-G gene in susceptibility to the disease

    Pre-eclampsia is a disorder of human pregnancy occuring in 5-10 % of all births, and represents the leading cause of infant morbidity and mortality and maternal death. In pre-eclampsia, invasion of fetal trop...

    M. O'Brien, T. McCarthy, D. Jenkins, P. Paul… in Cellular and Molecular Life Sciences CMLS (2001)

  6. No Access

    Chapter and Conference Paper

    Lipid Traffic to the Plasma Membrane of Leek Cells. Sorting Based on Fatty Acyl Chain Length

    The mechanisms by which lipids are sorted and transferred to the plasma membrane are poorly understood as compared to the situation of glyco- proteins but are now under intense investigations particularly in a...

    P. Moreau, B. Sturbois, L. Maneta-Peyret… in Molecular Mechanisms of Membrane Traffic (1993)

  7. No Access

    Chapter and Conference Paper

    Acyl Transfer Reactions Associated with Cis Golgi Apparatus

    Recent work in our laboratory involving cell-free lipid transfer from transitional endoplasmic reticulum (ER) to Golgi apparatus has shown a latent phospholipase A activity localized in the cis Golgi of rat li...

    J. B. Lawrence, T. W. Keenan, P. Moreau… in Molecular Mechanisms of Membrane Traffic (1993)

  8. No Access

    Article

    Cell-free transfer and sorting of membrane lipids in spinach

    The donor and acceptor specificity of cell-free transfer of radiolabeled membrane constituents, chiefly lipids, was examined using purified fractions of endoplasmic reticulum, Golgi apparatus, nuclei, plasma m...

    D. J. Morré, C. Penel, Dorothy M. Morré, Anna S. Sandelius, P. Moreau… in Protoplasma (1991)

  9. No Access

    Article

    Cell-free transfer of sterols from dictyosome-like structures to plasma membrane vesicles of guinea pig testes

    Transfer of radiolabeled lipids from dictyosome-like structures (DLS) from testis tubules of the guinea pig as donor to unlabeled plasma membrane from testis tubules immobilized on nitrocellulose as acceptor w...

    Lisette Waits, Stephanie Dunkle, F. E. Wilkinson, P. Moreau, Keri Safranski… in Protoplasma (1990)

  10. No Access

    Chapter

    Plasma Membrane Biogenesis in Higher Plants: The Lipid Routes

    The study of the biogenesis of the plasma membrane in higher plants has lagged behind that of animal cells, though the endomembrane concept, as well as the indications concerning the membrane traffic, resulted...

    C. Cassagne, R. Lessire, P. Moreau, J.-J. Bessoule… in Biological Role of Plant Lipids (1989)

  11. No Access

    Chapter

    Monensin: A Tool to Study Intracellular Transport of Lipids in Higher Plants

    The biogenesis of the plasma membrane has been extensively studied in both animal and plant cells by following the biosynthesis, maturation and intracellular transport of glycoproteins. However, little is yet ...

    P. Bertho, P. Moreau, Hélène Juguelin, C. Cassagne in Biological Role of Plant Lipids (1989)

  12. No Access

    Chapter

    Study of the Intracellular Transfer of Lipids to the Plasmalemma

    It has been shown in vitro that in leek (Allium porrum L.) epidermis cells very long chain fatty acids (VLCFA) are synthesized in the endoplasmic reticulum.1 Moreover, VLCFA are more abundant in the plasma membra...

    P. Moreau, H. Juguelin, R. Lessire… in The Metabolism, Structure, and Function of… (1987)