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  1. No Access

    Chapter

    Mucine-1 Is Related to Cell-Mediated Immunoexpression and Blood Pressure in Pulmonary Artery in Pulmonary Arterial Hypertension (PAH): Preliminary Results

    Background and aim : Mucine-1 (MUC1) increases in primary lung disease; however, no data are available on pulmonary arterial hypertension (PAH). Our aim was to analyze MUC1 in PAH and a possible link with pulmon...

    S. Cicco, P. Leone, V. Racanelli, A. Vacca in Oxygen Transport to Tissue XL (2018)

  2. Article

    Open Access

    Simian immunodeficiency virus-Vpx as an adjuvant for integrase defective lentiviral vector-based vaccines

    M Blasi, A Rossi, Z Michelini, P Leone, G Perretta, A Cimarelli… in Retrovirology (2012)

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  3. No Access

    Article

    Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes

    This study compared a range of mammalian CNS expression cassettes in recombinant adeno-associated virus (AAV-2) vectors using strong endogenous promoter sequences, with or without a strong post-regulatory elem...

    R Xu, CG Janson, M Mastakov, P Lawlor, D Young, A Mouravlev, H Fitzsimons… in Gene Therapy (2001)

  4. No Access

    Article

    In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector

    An adeno-associated virus (AAV) vector, expressing genes for human tyrosine hydroxylase (TH) and aromatic amino acid decarboxylase (AADC), demonstrated significantly increased production of dopamine in 293 (hu...

    MJ During, RJ Samulski, JD Elsworth, MG Kaplitt, P Leone, X **ao, J Li… in Gene Therapy (1998)

  5. No Access

    Article

    SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade?

    The influence of the D1 antagonist SCH 23390 on the motivational properties of rewarding (morphine, nicotine and diazepam) and aversive (naloxone, phencyclidine and picrotoxin) drugs was studied in the rat in a t...

    E. Acquas, E. Carboni, P. Leone, G. Di Chiara in Psychopharmacology (1989)

  6. No Access

    Article

    5HT3 receptor antagonists block morphine- and nicotine-but not amphetamine-induced reward

    The effect of two potent and specific antagonists of 5HT3 receptors, ICS 205-930 and MDL 72222, on the reinforcing properties of amphetamine, morphine and nicotine was studied in rats. Durg-induced reinforcement ...

    E. Carboni, E. Acquas, P. Leone, G. Di Chiara in Psychopharmacology (1989)