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    Article

    The EIF2AK3 gene region and type I diabetes in subjects from South India

    Mutations in the EIF2AK3 gene underlie susceptibility to the Wolcott–Rallison syndrome, which is a monogenic disease associated with insulin-deficient neonatal diabetes. Furthermore, suggestive evidence of linkag...

    R A Allotey, V Mohan, M F McDermott, R Deepa, G Premalatha, Z Hassan in Genes & Immunity (2004)

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    Article

    Genetic susceptibility to fibrocalculous pancreatic diabetes in Bangladeshi subjects: a family study

    Fibrocalculous pancreatic diabetes (FCPD) is an uncommon cause of diabetes, seen mainly in develo** countries. A family-based study was carried out in 67 Bangladeshi families, consisting of a proband with FC...

    Z Md Chowdhury, M F McDermott, S Davey, Z Hassan, P J Sinnott in Genes & Immunity (2002)

  3. Article

    Evidence that single nucleotide polymorphism in the uncoupling protein 3 (UCP3) gene influences fat distribution in women of European and Asian origin

    Aims/hypothesis. Uncoupling proteins are mitochondrial transmembrane carriers implicated in the regulation of energy balance. Dysfunction of UCP3 (the predominant uncoupling protein in skeletal m...

    P. G. Cassell, P. J. Saker, S. J. Huxtable, E. Kousta, A. E. Jackson in Diabetologia (2000)

  4. Article

    35th Annual Meeting of the European Association for the Study of Diabetes

    A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang in Diabetologia (1999)

  5. Article

    An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes

    Aims/hypothesis. Linkage between markers close to the uncoupling protein 2 and 3 genes (11q13) and resting metabolic rate and a pre-diabetic phenotype have been found. The syntenic region in mous...

    P. G. Cassell, M. Neverova, S. Janmohamed, N. Uwakwe, A. Qureshi in Diabetologia (1999)

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    Chapter and Conference Paper

    Primary Malignant Lymphoma of the Rectum Associated with Chronic Ulcerative Colitis

    Adenocarcinoma of the large bowel is well established as an important complication of chronic ulcerative colitis. The cumulative risk in patients with 25 years’ history of extensive colitis is about 9% [1]. Ho...

    A. L. Desai, P. G. Cassell in Updates in Colo-Proctology (1992)

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    Chapter

    HLA-DP Region Is Relevant to Celiac Disease Susceptibility

    Genes important in determining susceptibility to celiac disease (CD) are located within or near the HLA region. Associations were first described with Al and B8, and subsequently with DR3 and DR7. More recentl...

    M. J. Niven, C. Caffrey, J. A. Sachs, P. G. Cassell, R. Gallagher in Immunobiology of HLA (1989)

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    Article

    Adjuvant oral Razoxane (ICRF 159) in resectable colo-rectal cancer

    M. L. Slevin, V. J. Harvey, P. F. M. Wrigley in Cancer Chemotherapy and Pharmacology (1983)

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    Article

    Adjuvant oral razoxane (ICRF-159) in resectable colorectal cancer

    One hundred and seventy six patients (81 controls, 95 receiving treatment) have entered a prospective randomized tiral of long-term oral adjuvant razoxane (ICRF-159) following removal of a colorectal cancer. T...

    J. M. Gilbert, K. Hellmann, M. Evans, P. G. Cassell in Cancer Chemotherapy and Pharmacology (1982)