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Article
Evidence that single nucleotide polymorphism in the uncoupling protein 3 (UCP3) gene influences fat distribution in women of European and Asian origin
Aims/hypothesis. Uncoupling proteins are mitochondrial transmembrane carriers implicated in the regulation of energy balance. Dysfunction of UCP3 (the predominant uncoupling protein in skeletal m...
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Article
35th Annual Meeting of the European Association for the Study of Diabetes
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Article
An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes
Aims/hypothesis. Linkage between markers close to the uncoupling protein 2 and 3 genes (11q13) and resting metabolic rate and a pre-diabetic phenotype have been found. The syntenic region in mous...
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Chapter and Conference Paper
Primary Malignant Lymphoma of the Rectum Associated with Chronic Ulcerative Colitis
Adenocarcinoma of the large bowel is well established as an important complication of chronic ulcerative colitis. The cumulative risk in patients with 25 years’ history of extensive colitis is about 9% [1]. Ho...
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Article
Adjuvant oral Razoxane (ICRF 159) in resectable colo-rectal cancer
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Article
Adjuvant oral razoxane (ICRF-159) in resectable colorectal cancer
One hundred and seventy six patients (81 controls, 95 receiving treatment) have entered a prospective randomized tiral of long-term oral adjuvant razoxane (ICRF-159) following removal of a colorectal cancer. T...