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  1. Article

    Open Access

    Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer

    Impairment of the immune response and aberrant expression of microRNAs are emerging hallmarks of tumour initiation/progression, in addition to driver gene mutations and epigenetic modifications. We performed a...

    T Colangelo, G Polcaro, P Ziccardi, B Pucci, L Muccillo, M Galgani in Cell Death & Disease (2016)

  2. Article

    The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells

    Immunogenic cell death (ICD) evoked by chemotherapeutic agents implies emission of selected damage-associated molecular patterns (DAMP) such as cell surface exposure of calreticulin, secretion of ATP and HMGB1...

    T Colangelo, G Polcaro, P Ziccardi, L Muccillo, M Galgani, B Pucci in Cell Death & Disease (2016)