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  1. No Access

    Article

    Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes

    This study compared a range of mammalian CNS expression cassettes in recombinant adeno-associated virus (AAV-2) vectors using strong endogenous promoter sequences, with or without a strong post-regulatory elem...

    R Xu, CG Janson, M Mastakov, P Lawlor, D Young, A Mouravlev, H Fitzsimons… in Gene Therapy (2001)

  2. No Access

    Article

    In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector

    An adeno-associated virus (AAV) vector, expressing genes for human tyrosine hydroxylase (TH) and aromatic amino acid decarboxylase (AADC), demonstrated significantly increased production of dopamine in 293 (hu...

    MJ During, RJ Samulski, JD Elsworth, MG Kaplitt, P Leone, X **ao, J Li… in Gene Therapy (1998)