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TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1

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  1. Article

    Open Access

    MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

    MicroRNAs (miRNAs) comprise a class of short, non-coding RNAs that regulate protein synthesis through posttranscriptional modifications. In this study, we found significant upregulation of miR-18a in prostate ...

    T-I Hsu, C-H Hsu, K-H Lee, J-T Lin, C-S Chen, K-C Chang, C-YJ Su, M Hsiao in Oncogenesis (2014)

  2. Article

    Open Access

    WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β

    WW domain-containing oxidoreductase (WWOX), a putative tumour suppressor, is suggested to be involved in the hyperphosphorylation of Alzheimer's Tau. Tau is a microtubule-associated protein that has an importa...

    H-Y Wang, L-I Juo, Y-T Lin, M Hsiao, J-T Lin, C-H Tsai in Cell Death & Differentiation (2012)