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  1. Article

    Open Access

    A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations

    The incorporation of orthophosphate from scarce geochemical sources into the organic compounds essential for life under mild conditions is a fundamental challenge for prebiotic chemistry. Here we report a preb...

    Oliver R. Maguire, Iris B. A. Smokers, Wilhelm T. S. Huck in Nature Communications (2021)

  2. Article

    Open Access

    A catalytically active oscillator made from small organic molecules

    Oscillatory systems regulate many biological processes, including key cellular functions such as metabolism and cell division, as well as larger-scale processes such as circadian rhythm and heartbeat14. Abiotic ...

    Matthijs ter Harmsel, Oliver R. Maguire, Sofiya A. Runikhina, Albert S. Y. Wong in Nature (2023)