24 Result(s)
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Ola Hössjer
English
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Article
Open AccessThe representation, quantification, and nature of genetic information
Current genetics studies often refer to notions from information science. The purpose of this paper is to summarize and structure the different notions of information used in biology, as a step towards develop...
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Article
Open AccessErratum: Classification Under Partial Reject Options
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Article
Open AccessClassification Under Partial Reject Options
In many applications there is ambiguity about which (if any) of a finite number N of hypotheses that best fits an observation. It is of interest then to possibly output a whole set of categories, that is, a scena...
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Article
Open AccessEffects of subpopulation extinction on effective size (Ne) of metapopulations
Population extinction is ubiquitous in all taxa. Such extirpations can reduce intraspecific diversity, but the extent to which genetic diversity of surviving populations are affected remains largely unclear. A...
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Article
Open AccessAssessment of the Global Variance Effective Size of Subdivided Populations, and Its Relation to Other Effective Sizes
The variance effective population size ( \(N_{eV}\) N ...
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Article
Sometimes Size Does Not Matter
Recently Díaz, Hössjer and Marks (DHM) presented a Bayesian framework to measure cosmological tuning (either fine or coarse) that uses maximum entropy (maxent) distributions on unbounded sample spaces as prior...
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Reference Work Entry In depth
Dynamical Systems and Fitness Maximization in Evolutionary Biology
Five years after Charles Darwin put forward his theory of Natural Selection, Herbert Spencer coined the phrase “survival of the fittest.” Survival of the fittest implies that individuals with highest fitness w...
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Living Reference Work Entry In depth
Dynamical Systems and Fitness Maximization in Evolutionary Biology
Five years after Charles Darwin put forward his theory of Natural Selection, Herbert Spencer coined the phrase “survival of the fittest.” Survival of the fittest implies that individuals with highest fitness w...
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Chapter and Conference Paper
Dmitrii S. Silvestrov
This chapter presents short biographical notes about Professor Dmitri S. Silvestrov.
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Chapter and Conference Paper
Phase-Type Distribution Approximations of the Waiting Time Until Coordinated Mutations Get Fixed in a Population
In this paper we study the waiting time until a number of coordinated mutations occur in a population that reproduces according to a continuous time Markov process of Moran type. It is assumed that any individ...
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Chapter and Conference Paper
Continuous Approximations of Discrete Choice Models Using Point Process Theory
We analyze continuous approximations of discrete choice models with a large number of options. We start with a discrete choice model where agents choose between different options, and where each option is defi...
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Chapter and Conference Paper
Nonlinearly Perturbed Birth-Death-Type Models
Asymptotic expansions are presented for stationary and conditional quasi-stationary distributions of nonlinearly perturbed birth-death-type semi-Markov models, as well as for computing coefficients of ...
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Article
Open AccessThe interaction between smoking and HLA genes in multiple sclerosis: replication and refinement
Interactions between environment and genetics may contribute to multiple sclerosis (MS) development. We investigated whether the previously observed interaction between smoking and HLA genotype in the Swedish ...
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Article
Open AccessA significant risk locus on 19q13 for bipolar disorder identified using a combined genome-wide linkage and copy number variation analysis
The genetic background to bipolar disorder (BPD) has been attributed to different genetic and genomic risk factors. In the present study we hypothesized that inherited copy number variations (CNVs) contribute ...
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Article
Open AccessOn the eigenvalue effective size of structured populations
A general theory is developed for the eigenvalue effective size ( \(N_{eE}\) ...
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Article
Spatial Autocorrelation for Subdivided Populations with Invariant Migration Schemes
For populations with geographic substructure and selectively neutral genetic data, the short term dynamics is a balance between migration and genetic drift. Before fixation of any allele, the system enters int...
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Article
Quasi equilibrium, variance effective size and fixation index for populations with substructure
In this paper, we develop a method for computing the variance effective size \(N_{eV}\) ...
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Article
Open AccessThe genetic interacting landscape of 63 candidate genes in Major Depressive Disorder: an explorative study
Genetic contributions to major depressive disorder (MDD) are thought to result from multiple genes interacting with each other. Different procedures have been proposed to detect such interactions. Which approa...
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Chapter
Probabilistic Choice with an Infinite Set of Options: An Approach Based on Random Sup Measures
This chapter deals with probabilistic choice when the number of options is infinite. The choice space is a compact set $$S\subseteq \mathbb {R...
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Chapter
Analysis of the Stochasticity of Mortality Using Variance Decomposition
We analyse the stochasticity in mortality data from the USA, the UK and Sweden, and in particular to which extent mortality rates are explained by systematic variation, due to various risk factors, and random ...
