9 Result(s)
within
Nina Eikelis
English
-
Article
Open AccessInvestigating the relationship between early cardiovascular disease markers and loneliness in young adults
Loneliness is recognised as a risk factor for cardiovascular disease development. However, it is unclear whether loneliness itself or other closely related mental health symptoms, such as depression and social...
-
Article
Open AccessPlasma lipocalin-2/NGAL is stable over 12 weeks and is not modulated by exercise or dieting
Amongst other immune cells, neutrophils play a key role in systemic inflammation leading to cardiovascular disease and can release inflammatory factors, including lipocalin-2 (LCN2). LCN2 drives cardiac hypert...
-
Article
Empagliflozin modulates renal sympathetic and heart rate baroreflexes in a rabbit model of diabetes
We determined whether empagliflozin altered renal sympathetic nerve activity (RSNA) and baroreflexes in a diabetes model in conscious rabbits.
-
Article
Correction to: Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans
The baseline insulin data given in Table 1 for the placebo group were incorrectly reported as 51 ± 10 pmol/l instead of 48 ± 10 pmol/l. This mistake also impacts on data reported in Table 4.
-
Article
Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans
Increasing brown adipose tissue (BAT) activity is a possible therapeutic strategy to increase energy expenditure and glucose and lipid clearance to ameliorate obesity and associated comorbidities. The thiazoli...
-
Article
Open AccessP175: An Acute Bout of Prolonged Sitting Impairs Endothelial Function and Increases Plasma Concentrations of Endothelin-1 In
Compared to regular active breaks, prolonged uninterrupted sitting amplifies postprandial glucose and insulin in overweight/obese adults with and without type 2 diabetes; and impairs lower limb endothelial fun...
-
Article
Open AccessReduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss
The hyperinsulinemia of obesity is a function of both increased pancreatic insulin secretion and decreased insulin clearance, and contributes to cardiovascular risk. Whilst weight loss is known to enhance insu...
-
Article
Chronic ephedrine administration decreases brown adipose tissue activity in a randomised controlled human trial: implications for obesity
Brown adipose tissue (BAT) activation increases energy expenditure and may have therapeutic potential to combat obesity. The primary activating and adaptive signal for BAT is via β-adrenergic signalling. We pr...
-
Article
Progression of cardiovascular and endocrine dysfunction in a rabbit model of obesity
In rabbits, mean arterial pressure (MAP) increases in response to fat feeding, but does not increase further with progressive weight gain. We documented the progression of adiposity and the alterations in endo...
