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  1. No Access

    Article

    MicroRNA-132 may be associated with blood pressure and liver steatosis—preliminary observations in obese individuals

    Recent findings in experimental models have shown that the microRNA miR-132 (mir-132) is an important regulator of liver homeostasis and lipid metabolism. We aimed to assess miR-132 expression in liver and fat...

    Nina Eikelis, John B. Dixon, Elisabeth A. Lambert… in Journal of Human Hypertension (2022)

  2. No Access

    Article

    Neural suppression of miRNA-181a in the kidney elevates renin expression and exacerbates hypertension in Schlager mice

    BPH/2J mice are a genetic model of hypertension with overactivity of the sympathetic nervous system (SNS) and renin–angiotensin system (RAS). BPH/2J display higher renal renin mRNA and low levels of its negati...

    Kristy L. Jackson, Cindy Gueguen, Kyungjoon Lim, Nina Eikelis… in Hypertension Research (2020)

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    Article

    Renal nerves contribute to hypertension in Schlager BPH/2J mice

    Schlager mice (BPH/2J) are hypertensive due to a greater contribution of the sympathetic nervous system (SNS) and renin-angiotensin system (RAS). The kidneys of BPH/2J are hyper-innervated suggesting renal ner...

    Cindy Gueguen, Kristy L. Jackson, Francine Z. Marques… in Hypertension Research (2019)

  4. Article

    Progression of cardiovascular and endocrine dysfunction in a rabbit model of obesity

    In rabbits, mean arterial pressure (MAP) increases in response to fat feeding, but does not increase further with progressive weight gain. We documented the progression of adiposity and the alterations in endo...

    Gabriela A Eppel, James A Armitage, Nina Eikelis, Geoffrey A Head… in Hypertension Research (2013)

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    Chapter

    The Brain and Leptin Resistance and Implications for Food-Related Disorders

    Obesity and the chronic diseases associated with obesity are rapidly becoming a public health crisis in the world. The existence of a circulating factor with effects on body weight has long been anticipated. T...

    Nina Eikelis, Gavin Lambert in Handbook of Behavior, Food and Nutrition (2011)