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    Article

    Hyperparameter autotuning of programs with HybridTuner

    Algorithms must often be tailored to a specific architecture and application in order to fully harness the capabilities of sophisticated computer architectures and computational implementations. However, the r...

    Benjamin Sauk, Nikolaos V. Sahinidis in Annals of Mathematics and Artificial Intelligence (2023)

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    Chapter and Conference Paper

    Heat Exchanger Circuitry Design by Decision Diagrams

    The interconnection pattern between the tubes of a tube-fin heat exchanger, also referred to as its circuitry, has a significant impact on its performance. We can improve the performance of a heat exchanger by...

    Nikolaos Ploskas, Christopher Laughman in Integration of Constraint Programming, Art… (2019)

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    Article

    Domain reduction techniques for global NLP and MINLP optimization

    Optimization solvers routinely utilize presolve techniques, including model simplification, reformulation and domain reduction techniques. Domain reduction techniques are especially important in speeding up co...

    Yash Puranik, Nikolaos V. Sahinidis in Constraints (2017)

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    Chapter and Conference Paper

    A Branch-and-Reduce Algorithm for the Contact Map Overlap Problem

    A fundamental problem in molecular biology is the comparison of 3-dimensional protein folds in order to develop similarity measures and exploit them for protein clustering, database searches, and drug design. ...

    Wei **e, Nikolaos V. Sahinidis in Research in Computational Molecular Biology (2006)