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    Transcriptional Regulation of the GLAST/EAAT-1 Gene in Rat and Man

    Various acute and chronic brain diseases result in disturbed expression of the glial glutamate transporters, GLAST/EAAT-1 and GLT-1/EAAT-2, and subsequent secondary neuronal cell death. The idea that glutamate...

    Tina Unger, Nicole Lakowa, Stefanie Bette in Cellular and Molecular Neurobiology (2012)

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    Sequences of the Non-Coding RNA, NTAB, are Contained within the 3′-UTR of Human and Rat EAAT2/GLT-1 Transcripts and Act as Transcriptional Enhancers

    In the CNS, extracellular glutamate is predominantly cleared by astroglial cells through the high-affinity glutamate transporter subtype, EAAT2/GLT-1. Expression of EAAT2/GLT-1 is perturbed in various acute an...

    Stefanie Bette, Tina Unger, Nicole Lakowa in Cellular and Molecular Neurobiology (2011)