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  1. Article

    Open Access

    A systematic review and meta-analysis investigating the relationship between metabolic syndrome and the incidence of thyroid diseases

    To assess the prospective association between metabolic syndrome (MetS), its components, and incidence of thyroid disorders by conducting a systematic review and meta-analysis.

    Heba Alwan, Valerie Aponte Ribero, Orestis Efthimiou, Cinzia Del Giovane in Endocrine (2024)

  2. Article

    Open Access

    Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial

    Several trials and meta-analyses found a benefit of adjunct corticosteroids for community-acquired pneumonia with respect to short-term outcome, but there is uncertainty about longer-term health effects. Herei...

    Claudine A. Blum, Eva A. Roethlisberger, Nicole Cesana-Nigro in BMC Pulmonary Medicine (2023)

  3. Article

    Open Access

    Seroprevalence trends of anti-SARS-CoV-2 antibodies and associated risk factors: a population-based study

    We aimed to assess the seroprevalence trends of SARS-CoV-2 antibodies in several Swiss cantons between May 2020 and September 2021 and investigate risk factors for seropositivity and their changes over time.

    Stefano Tancredi, Arnaud Chiolero, Cornelia Wagner, Moa Lina Haller in Infection (2023)

  4. Article

    Open Access

    Benzodiazepine Receptor Agonists Use and Cessation Among Multimorbid Older Adults with Polypharmacy: Secondary Analysis from the OPERAM Trial

    Benzodiazepine receptor agonists (BZRAs) are commonly prescribed in older adults despite an unfavorable risk–benefit ratio. Hospitalizations may provide a unique opportunity to initiate BZRA cessation, yet lit...

    François-Xavier Sibille, Marie de Saint-Hubert, Séverine Henrard in Drugs & Aging (2023)

  5. Article

    Open Access

    HOSPITAL Score and LACE Index to Predict Mortality in Multimorbid Older Patients

    Estimating life expectancy of older adults informs whether to pursue future investigation and therapy. Several models to predict mortality have been developed but often require data not immediately available d...

    Carole E. Aubert, Nicolas Rodondi, Samuel W. Terman, Martin Feller in Drugs & Aging (2022)

  6. Article

    Open Access

    Frequency and Acceptance of Clinical Decision Support System-Generated STOPP/START Signals for Hospitalised Older Patients with Polypharmacy and Multimorbidity

    The Screening Tool of Older Persons’ Prescriptions (STOPP)/Screening Tool to Alert to Right Treatment (START) instrument is used to evaluate the appropriateness of medication in older people. STOPP/START crite...

    Bastiaan T. G. M. Sallevelt, Corlina J. A. Huibers, Jody M. J. Op Heij in Drugs & Aging (2022)

  7. No Access

    Article

    Aspirin for the primary prevention of cardiovascular disease a comprehensive review

    Aspirin use for the primary prevention of cardiovascular disease should be targeted to patients with a high cardiovascular risk. Physicians should assess the risks and benefits of aspirin therapy for primary p...

    Nicolas Rodondi, Jacques Cornuz, Douglas C. Bauer in Comprehensive Therapy (2005)