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    Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells

    Gemcitabine is a potent inhibitor of DNA replication and is a mainstay therapeutic for diverse cancers, particularly pancreatic ductal adenocarcinoma (PDAC). However, most tumors remain refractory to gemcitabi...

    Ta**der Ubhi, Olga Zaslaver, Andrew T. Quaile, Dennis Plenker… in Nature Cancer (2024)