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Article
Open AccessWhite matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging
Supported by histological and genetic evidence implicating myelin, neuroinflammation and oligodendrocyte dysfunction in schizophrenia spectrum disorders (SZ), diffusion tensor imaging (DTI) studies have consis...
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Article
Open AccessWhite matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury
Identifying patients at risk of poor outcome after mild traumatic brain injury (MTBI) is essential to aid prognostics and treatment. Diffuse axonal injury (DAI) may be the primary pathologic feature of MTBI bu...
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Article
Open AccessDissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer’s disease spectrum
Recent efforts using diffusion tensor imaging (DTI) have documented white matter (WM) alterations in Alzheimer’s disease (AD). The full potential of whole-brain DTI, however, has not been fully exploited as st...
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Article
Open AccessNovel genetic loci associated with hippocampal volume
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are foun...
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Article
Open AccessDisrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer’s disease continuum
As findings on the neuropathological and behavioral components of Alzheimer’s disease (AD) continue to accrue, converging evidence suggests that macroscale brain functional disruptions may mediate their associ...