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Article
Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines
Metastasis suppressor genes (MSGs) have contributed to an understanding of regulatory pathways unique to the lethal metastatic process. When re-expressed in experimental models, MSGs block cancer spread to, an...
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Article
RNAi quashes polyQ
RNA interference in the brain inhibits neurodegeneration in a polyglutamine disease, SCA1. Is this now the way forward for the clinical treatment of certain genetic disorders (pages 816–820
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Article
Book reviews
An Introduction to Recombinant DNA in Medicine (2nd edn).
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Article
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
We report the results of a double-blind, placebo-controlled trial in nine cystic fibrosis (CF) subjects receiving cationic liposome complexed with a complementary DNA encoding the CF transmembrane conductance ...