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  1. No Access

    Chapter

    Status of Organophosphate Esters in the Environment of Develo** Countries and Their Impact on Human Health

    The presence of organophosphate ester (OPEs) in the environment of develo** countries has been reviewed in the current chapter. The strict regulations about the manufacturing and usage of flame retardants (F...

    Nadeem Ali, Muhammad Imtiaz Rashid, Nabil A. Alhakamy in Electronic Waste Pollution (2019)

  2. No Access

    Chapter

    New Brominated Flame Retardants in the Environment of Develo** Countries

    The environmental occurrence of new brominated flame retardants (NBFRs) in the emerging economies has been reviewed in the current chapter. The strict regulations about the manufacturing and usage of polybromi...

    Nadeem Ali, Khurram Shahzad, Ehtisham Nazar in Electronic Waste Pollution (2019)

  3. No Access

    Article

    RETRACTED ARTICLE: Anti-tumor effect of PEG-coated PLGA nanoparticles of febuxostat on A549 non-small cell lung cancer cells

    In the present study, febuxostat (FBX)-loaded PEG-coated PLGA nanoparticles (FBX–PLGA–PEG) were developed and its anticancer activity on lung cancer cells was evaluated. FBX–PLGA–PEG were prepared by nanopreci...

    Mohammad Y. Alfaifi, Ali A. Shati, Serag Eldin I. Elbehairi, Usama A. Fahmy in 3 Biotech (2020)

  4. No Access

    Article

    RETRACTED ARTICLE: ArticleNoteOptimization of Thymoquinone-Loaded Coconut Oil Nanostructured Lipid Carriers for the Management of Ethanol-Induced Ulcer

    In the global incidence of peptic ulcer, with the associated rates of hospitalizations and mortality are increasing, in the United States, peptic ulcer disease affects approximately 4.6 million people annually...

    Usama A. Fahmy, Ahmed L. Alaofi, Zuhier A. Awan, Hani M. Alqarni in AAPS PharmSciTech (2020)

  5. No Access

    Article

    Formulation of Chitosan Polymeric Vesicles of Ciprofloxacin for Ocular Delivery: Box-Behnken Optimization, In Vitro Characterization, HET-CAM Irritation, and Antimicrobial Assessment

    Ciprofloxacin is a commonly used antibiotic for treatment of bacterial conjunctivitis. The conventional eye drop dosage form is the widely used mode of treatment, but it has low corneal residence time. This dr...

    Ameeduzzafar, Nabil K Alruwaili, Syed Sarim Imam in AAPS PharmSciTech (2020)

  6. Article

    Correction to: Optimization of Thymoquinone-Loaded Coconut Oil Nanostructured Lipid Carriers for the Management of Ethanol-Induced Ulcer

    When the article was first published, the incorrect image for Fig. 1 was inadvertently uploaded.

    Usama A. Fahmy, Ahmed L. Alaofi, Zuhier A. Awan, Hani M. Alqarni in AAPS PharmSciTech (2020)

  7. No Access

    Chapter

    Screening of Herbal Medicines for Neurotoxicity: Principles and Methods

    Although there are some benefits derived from the use of medicinal herbs as remedies, some of them are associated with neurological adverse effects. Such potential hazards could be caused by several factors, i...

    Alshaimaa M. Almehmady, Nabil A. Alhakamy, Waleed S. Alharbi in Medicinal Herbs and Fungi (2021)

  8. No Access

    Article

    Arsenic and lead in the indoor residential settings of different socio-economic status; assessment of human health risk via dust exposure

    In the present study, occurrence of arsenic (As) and lead (Pb) is reported in rural and urban household dust (floor and AC filter dust) of the Kingdom of Saudi Arabia (KSA). Several studies have found concerni...

    Nadeem Ali in Environmental Science and Pollution Resear… (2021)

  9. Article

    Open Access

    Formulation and evaluation of injectable dextran sulfate sodium nanoparticles as a potent antibacterial agent

    The purpose of this study was to develop a novel nano antibacterial formulation of dextran sulfate sodium polymer. The dextran sulfate sodium (DSS) nanoparticles were formulated with gelation technique. The na...

    Osama A. Madkhali, Sivakumar Sivagurunathan Moni, Muhammad H. Sultan in Scientific Reports (2021)

  10. No Access

    Article

    Brucine-loaded transliposomes nanogel for topical delivery in skin cancer: statistical optimization, in vitro and dermatokinetic evaluation

    The aim of the present study was to develop, optimize brucine-loaded transliposomes (BRC-TL) formulation for dermal delivery of brucine for skin cancer. The BRC-TL formulations were evaluated for vesicle size,...

    Nabil A. Alhakamy, Hibah M. Aldawsari, Javed Ali, Dipak K. Gupta in 3 Biotech (2021)

  11. No Access

    Article

    RETRACTED ARTICLE: Fluvastatin-Loaded Emulsomes Exhibit Improved Cytotoxic and Apoptosis in Prostate Cancer Cells

    Fluvastatin (FLV) is known to inhibit the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA), which is over-expressed in various cancers. FLV has been reported to decrease cancer development and metastasis. Howev...

    Nabil A. Alhakamy, Shaimaa M. Badr-Eldin, Hibah M. Aldawsari in AAPS PharmSciTech (2021)

  12. No Access

    Article

    RETRACTED ARTICLE: Development and Evaluation of Icariin-Loaded PLGA-PEG Nanoparticles for Potentiation the Proapoptotic Activity in Pancreatic Cancer Cells

    Therapeutic efficacy of antineoplastic agents possessing a selective target to the nucleus of the cancer cells could be enhanced through novel formulation approaches. Thus, towards improvement of anticancer po...

    Nabil A. Alhakamy in AAPS PharmSciTech (2021)

  13. Article

    Open Access

    Characterization of cisplatin-loaded chitosan nanoparticles and rituximab-linked surfaces as target-specific injectable nano-formulations for combating cancer

    The present study was carried out to develop cisplatin-loaded chitosan nanoparticles (CCNP) and cisplatin-loaded chitosan nanoparticle surface linked to rituximab (mAbCCNP) as targeted delivery formulations. T...

    Muhammad H. Sultan, Sivakumar S. Moni, Osama A. Madkhali in Scientific Reports (2022)

  14. Article

    Open Access

    Hybrid nanoparticulate system of Fluvastatin loaded phospholipid, alpha lipoic acid and melittin for the management of colon cancer

    As a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, Fluvastatin (FLV) is used for reducing low-density lipoprotein (LDL) cholesterol as well as to prevent cardiovascular problems. FLV showed c...

    Mohamed A. Alfaleh, Omar Fahmy, Mohammed W. Al-Rabia in Scientific Reports (2022)

  15. Article

    Open Access

    A window of opportunity trial evaluating intratumoral injection of Copaxone® in patients with percutaneously accessible tumors

    This window of opportunity trial evaluated the safety of intratumoral Copaxone® and profiled immune markers in biopsies before and after treatment.

    Joaquina C. Baranda, Ghulam Rehman Mohyuddin in Translational Medicine Communications (2023)

  16. No Access

    Article

    Design of Experiment Navigated Methodical Development of Neem Oil Nanoemulsion Containing Tea Tree Oil for Dual Effect Against Dermal Illness: Ex Vivo Dermatokinetic and In Vivo

    This study was designed to develop neem oil nanoemulsion of tea tree oil (TTO-NO-NE) using design of experiment based Box–Behnken design, which provided thermodynamic stable NE with globule size of 174 nm, and...

    Hani Z. Asfour, Nabil A. Alhakamy, Md Shoaib Alam in Journal of Cluster Science (2023)

  17. Article

    Retraction Note: Optimization of Thymoquinone-Loaded Coconut Oil Nanostructured Lipid Carriers for the Management of Ethanol-Induced Ulcer

    Usama A. Fahmy, Ahmed L. Alaofi, Zuhier A. Awan, Hani M. Alqarni in AAPS PharmSciTech (2023)

  18. Article

    Retraction Note: Fluvastatin-Loaded Emulsomes Exhibit Improved Cytotoxic and Apoptosis in Prostate Cancer Cells

    Nabil A. Alhakamy, Shaimaa M. Badr-Eldin, Hibah M. Aldawsari in AAPS PharmSciTech (2023)

  19. Article

    Retraction Note: Development and Evaluation of Icariin-Loaded PLGA-PEG Nanoparticles for Potentiation the Proapoptotic Activity in Pancreatic Cancer Cells

    Nabil A. Alhakamy in AAPS PharmSciTech (2023)

  20. Article

    Correction: Incorporating sodium deoxycholate endorsed the buccal administration of avanafil to heighten the bioavailability and duration of action

    Khalid M. El-Say, Omar D. Al-hejaili in Drug Delivery and Translational Research (2023)

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