14 Result(s)

Article

Common rs7138803 variant of FAIM2 and obesity in Han Chinese

Obesity causes severe healthcare problem worldwide leading to numerous diseases, such as cardiovascular diseases and diabetes mellitus. Previous Genome-Wide Association Study (GWAS) identified an association b...

Cong Li, Xue** Qiu, Na Yang, Jiajia Gao, Yuan Rong… in BMC Cardiovascular Disorders (2013)

Article

Semaphorin 3A attenuates cardiac autonomic disorders and reduces inducible ventricular arrhythmias in rats with experimental myocardial infarction

To investigate the effects of semaphorin 3A (sema 3A) on cardiac autonomic regulation and subsequent ventricular arrhythmias (VAs) in post-infarcted hearts.

Hesheng Hu, Yongli Xuan, Mei Xue, Wenjuan Cheng, Ye Wang… in BMC Cardiovascular Disorders (2016)

Article

In vitro assessment of the glucose-lowering effects of berberrubine-9-O-β-D-glucuronide, an active metabolite of berberrubine

Berberrubine (BRB) is the primary metabolite of berberine (BBR) that has shown a stronger glucose-lowering effect than BBR in vivo. On the other hand, BRB is quickly and extensively metabolized into berberrubine-...

Na Yang, Run-bin Sun, **ng-long Chen, Le Zhen, Chun Ge… in Acta Pharmacologica Sinica (2017)

Article

Are there too many screw holes in plates for fracture fixation?

Implant breakage after the fixation of traumatic fractures is rare; however, when it occurs, it is debilitating for the patients and a challenge for surgeons. The purpose of this study was to analyze and ident...

Hongzhi Lv, Wenli Chang, Peizhi Yuwen, Na Yang, **aoli Yan, Yingze Zhang in BMC Surgery (2017)

Article

Implementation of a Reference-Scaled Average Bioequivalence Approach for Highly Variable Acetylsalicylic Acid in Fixed-Dose Combination with Clopidogrel Versus Enteric Aspirin in Chinese Subjects Under Fasting Conditions: A Phase 1, Open-Label, Randomized, Crossover Study

Dual antiplatelet therapy, aspirin and a P2Y₁₂ inhibitor, is recommended to prevent thrombotic complications of acute coronary syndrome. Clopidogrel plus acetylsalicylic acid combination is the most commonly used...

Lu Wang, Yu**g Di, Tingting Guo, Jeffrey E. Ming, Fangyuan Kong… in Advances in Therapy (2020)

Article

Admission fasting plasma glucose is associated with in-hospital outcomes in patients with acute coronary syndrome and diabetes: findings from the improving Care for Cardiovascular Disease in China - Acute Coronary Syndrome (CCC-ACS) project

The discrepancy between glycosylated hemoglobin (HbA_1c) and fasting plasma glucose (FPG) in clinical practice may be related to factors such as acute stress, renal dysfunction, and anemia, and its relationship wi...

Nan Ye, Lijiao Yang, Guoqin Wang, Wei**g Bian, Fengbo Xu… in BMC Cardiovascular Disorders (2020)

Article

Subpopulation Differences in the Cardiovascular Efficacy of Long-Acting Glucagon-Like Peptide 1 Receptor Agonists in Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis

The cardiovascular efficacy of glucagon-like peptide 1 receptor agonists (GLP-1RAs) in type 2 diabetes mellitus (T2DM) are well documented; however, the differences in cardiovascular efficacy among subpopulati...

Liyun He, Na Yang, Lingling Xu, Fan **, Wei Li, Yuxiu Li… in Diabetes Therapy (2020)

Article

Bioequivalence Study Comparing Fixed-Dose Combination of Clopidogrel and Aspirin with Coadministration of Individual Formulations in Chinese Subjects Under Fed Conditions: A Phase I, Open-Label, Randomized, Crossover Study

Simultaneous administration of acetylsalicylic acid (ASA) and clopidogrel has demonstrated efficacy in the treatment of acute coronary syndrome. Clopidogrel + ASA in a fixed-dose combination (FDC) provides a p...

Yan Li, Jeffrey E. Ming, Fangyuan Kong, Huiqiu Yin, Linlin Zhang… in Advances in Therapy (2020)

Article

The association between atrial fibrillation and in-hospital outcomes in chronic kidney disease patients with acute coronary syndrome: findings from the improving care for cardiovascular disease in China-acute coronary syndrome (CCC-ACS) project

Atrial fibrillation (AF) is the most common cardiac arrhythmia in patients with chronic kidney disease (CKD) and acute coronary syndrome (ACS). This study aimed to explore the frequency and impact of AF on cli...

Lijiao Yang, Nan Ye, Guoqin Wang, Wei**g Bian, Fengbo Xu… in BMC Cardiovascular Disorders (2021)

Article

Correction to: Admission fasting plasma glucose is associated with in-hospital outcomes in patients with acute coronary syndrome and diabetes: findings from the improving Care for Cardiovascular Disease in China - Acute Coronary Syndrome (CCC-ACS) project

Nan Ye, Lijiao Yang, Guoqin Wang, Wei**g Bian, Fengbo Xu… in BMC Cardiovascular Disorders (2021)

Article

Mild renal insufficiency and attributable risk of adverse In-hospital outcomes in patients with Acute Coronary Syndrome from the improving care for Cardiovascular Disease in China (CCC) project

Renal insufficiency (RI) is a frequent comorbidity among patients with acute coronary syndrome (ACS). We aimed to evaluate the attributable risk associated with mild RI for the in-hospital outcomes in patients...

Fengbo Xu, Guoqin Wang, Nan Ye, Wei**g Bian, Lijiao Yang, Changsheng Ma… in BMC Nephrology (2022)

Article

Effect of intratracheal dexmedetomidine combined with ropivacaine on postoperative sore throat: a prospective randomised double-blinded controlled trial

The present study aimed to investigate whether intratracheal dexmedetomidine combined with ropivacaine reduces the severity and incidence of postoperative sore throat after tracheal intubation under general an...

**gyi Niu, Rui Hu, Na Yang, Yan He, Hao Sun, Rende Ning, Junma Yu in BMC Anesthesiology (2022)

Article

A Bioequivalence Study of Ezetimibe/Rosuvastatin Fixed Dose Combination (10 mg/10 mg) Versus the Individual Formulations Taken Concomitantly

This study evaluated the bioequivalence of ezetimibe/rosuvastatin fixed dose combination compared to the concomitant administration of individual formulations (ezetimibe and rosuvastatin) in Chinese healthy su...

Yu**g Di, Zhaojun Wang, Chuandong Jia, **n **e, Shanshan Yang… in Advances in Therapy (2023)

Article

Pharmacokinetics and Safety of iGlarLixi in Healthy Chinese Participants: Results of a Phase 1 Randomized Study

The Chinese Diabetes Society recommends basal insulin and glucagon-like peptide-1 receptor agonists as an add-on therapy to first-line oral antihyperglycemic drugs for people with type 2 diabetes (T2D). Fixed-...

Panpan **e, Xuemei He, **n Gao, Mengmeng Shuai, Wolfgang Schmider… in Diabetes Therapy (2023)