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Design, synthesis, characterization, and docking studies of hiherto unkown chlorinated thiazolidine, thiophene, and 2-iminochromene derivatives as protein-like protease inhibitors

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  1. Article

    Open Access

    In silico-guided discovery and in vitro validation of novel sugar-tethered lysinated carbon nanotubes for targeted drug delivery of doxorubicin

    Multiwalled carbon nanotubes (MWCNTs) functionalized with lysine via 1,3-dipolar cycloaddition and conjugated to galactose or mannose are potential nanocarriers that can effectively bind to the lectin receptor...

    Chanchal Kiran Thakur, Fábio G. Martins in Journal of Molecular Modeling (2024)

  2. Article

    Open Access

    Aggregation behaviour of radiolytically degraded diglycolamide based solvent system

    The 0.1 M TODGA + 0.2 M DOHyA/n-DD phase was irradiated to various absorbed dose levels and the extraction behaviour of nitric acid and Nd(III) in the irradiated organic phases were studied. The organic phase was...

    N. Parvathy, Jammu Ravi, N. Desigan in Journal of Radioanalytical and Nuclear Che… (2024)

  3. Article

    Open Access

    Corrosion resistance of aluminum against acid activation in 1.0 M HCl by symmetrical ball − type zinc phthalocyanine

    The inhibition effect of symmetrical Ball − type Zinc Phthalocyanine on Aluminum in 1mol/L hydrochloric acid was analyzed by electrochemical techniques. A novel ball-type zinc phthalocyanine (Zn-Pc) inhibitor ...

    Najah F. H. Alrasheedi, Ismail Abdulazeez, Shamsuddeen A. Haladu in BMC Chemistry (2024)

  4. Article

    Open Access

    A Comprehensive Investigation of Nanocomposite Polymer Flooding at Reservoir Conditions: New Insights into Enhanced Oil Recovery

    Recently, the polymer-nanoparticle combination has garnered significant interest in enhanced oil recovery (EOR) due to its promising experimental results. However, the previous research was mostly directed at ...

    Khalaf G. Salem, Adel M. Salem in Journal of Polymers and the Environment (2024)

  5. Article

    Open Access

    Map** a sustainable approach: biosynthesis of lactobacilli-silver nanocomposites using whey-based medium for antimicrobial and bioactivity applications

    This study explores a sustainable approach for synthesizing silver nanocomposites (AgNCs) with enhanced antimicrobial and bioactivity using safe Lactobacillus strains and a whey-based medium (WBM). WBM effectivel...

    E. B. El.Fadly, A. S. Salah, B. Abdella, A. Al Ali in Microbial Cell Factories (2024)

  6. Article

    Open Access

    Develo** and testing personalised nutrition feedback for more sustainable healthy diets: the MyPlanetDiet randomised controlled trial protocol

    Agriculture and food production contribute to climate change. There is mounting pressure to transition to diets with less environmental impact while maintaining nutritional adequacy. MyPlanetDiet aimed to redu...

    Katie P. Davies, Eileen R. Gibney, Ursula M. Leonard in European Journal of Nutrition (2024)

  7. Article

    Open Access

    Nutritional composition, fatty acids, bioactive compounds, and antioxidant activity of Nigella sativa seed grown in Bangladesh

    Black cumin seeds are extensively utilized for foods, cosmetics, and medicinal purposes. The current investigation was undertaken to analyzse the nutritional values, fatty acid compositions, bioactive compound...

    M. S. Hossain, M. Z. Rahman, S. N. Mozumder, J. Rahman in Discover Food (2024)

  8. Article

    Open Access

    Evaluation of the environmental and economic scope of an electrocoagulation process for the treatment of wastewater from the instant coffee industry

    In this study, an industrial wastewater from instant coffee production was treated by electrocoagulation (EC). The effect of various EC operating parameters, such as electrode type, current density, support el...

    Izabela Dobrosz-Gómez, Harold N. Ibarra-Taquez in Journal of Solid State Electrochemistry (2024)

  9. Article

    Open Access

    Effect of loading rate and pH on glycerol fermentation and microbial population in an upflow anaerobic filter reactor

    A reactor with silicone tubes as support medium was used for glycerol fermentation. The experimental set-up consisted of three phases. In P1, the applied glycerol loading rate (gly-LR) was in the range of 6–10...

    Cândida N. Cordeiro, Patricia Rojas in Bioprocess and Biosystems Engineering (2024)

  10. Article

    Open Access

    Hydrogenation of Cinnamaldehyde Using Carbon Dots Reduced Palladium Nanoparticles

    Carbon dots (CDs) with a size range of 0.2 to 2 nm were prepared using a hydrothermal treatment of sucrose and oleic acid. The as-synthesized CDs were used to reduce H2PdCl4 to metallic Pd nanoparticles with dPd ...

    Alice Magubane, Prakash M. Gangatharan, Pumza Mente in Catalysis Letters (2024)

  11. Article

    Open Access

    Porphyrin-fused graphene nanoribbons

    Graphene nanoribbons (GNRs), nanometre-wide strips of graphene, are promising materials for fabricating electronic devices. Many GNRs have been reported, yet no scalable strategies are known for synthesizing G...

    Qiang Chen, Alessandro Lodi, Heng Zhang, Alex Gee, Hai I. Wang in Nature Chemistry (2024)

  12. Article

    Open Access

    A de novo designed coiled coil-based switch regulates the microtubule motor kinesin-1

    Many enzymes are allosterically regulated via conformational change; however, our ability to manipulate these structural changes and control function is limited. Here we install a conformational switch for all...

    Jessica A. Cross, William M. Dawson, Shivam R. Shukla in Nature Chemical Biology (2024)

  13. Article

    Open Access

    Biosynthesis of TiO2 nano particles by using Rosemary (Rosmarinus officinalis) leaf extracts and its application for crystal dye degradation under sunlight

    Titanium dioxide (TiO2) nanoparticles were prepared through Rosmarinus-officinalis leaf extracts at 90 and 200°C. In this research, the degradations of methylene blues by using TiO2 nanoparticles Sun light radiat...

    Abel Saka, Leta Tesfaye Jule, Bayissa Badassa, Lamessa Gudata in BMC Chemistry (2024)

  14. Article

    Correction to: Computational Investigation on Tunability of Optical Absorption in MoS2 Integrated with Mono‑ and Non‑Alloyed AuAg Nanoparticles for Photodetector Application

    Anushkannan N. K., Uziel Boaz, Shubhashri Waghmare, Rozalina Zakaria in Plasmonics (2024)

  15. Article

    Open Access

    Synthesis, biological evaluation, and molecular docking of novel 1,3,4-substituted-thiadiazole derivatives as potential anticancer agent

    In an attempt to develop potent anti-cancer agents, a new 1,3,4-substituted-thiadiazole derivatives (8b-g), starting from 4-substituted-thiazol-2-chloroacetamides (4b-g), were synthesized and evaluated for their ...

    Samin A. Shaikh, Satish N. Wakchaure, Shivaji R. Labhade, Raju R. Kale in BMC Chemistry (2024)

  16. Article

    Open Access

    Utilization of macroporous beads impregnated with Cyanex 572 for effective separation of Sr(II), Y(III), and Zr(IV) from chloride medium: batch and fixed-bed column study

    This work focuses on using a new, inexpensive adsorbent, Amberlite XAD–4 resin impregnated with Cyanex 572 to extract and separate Zr(IV) from its parents Y(III) and Sr(II). The extraction performance was inve...

    Sh. Sh. Emam, R. Gamal, N. E. El-Hefny in Journal of Radioanalytical and Nuclear Chemistry (2024)

  17. Article

    Open Access

    Exploring ocean pH dynamics via a mathematical modeling with the Caputo fractional derivative

    Global warming is a complex problem with far-reaching global implications. One of its notable repercussions is the escalation of \(CO_2\) ...

    Manisha Krishna Naik, Chandrali Baishya in Journal of Umm Al-Qura University for Appl… (2024)

  18. Article

    Open Access

    Direct formation of copper nanoparticles from atoms at graphitic step edges lowers overpotential and improves selectivity of electrocatalytic CO2 reduction

    A key strategy for minimizing our reliance on precious metals is to increase the fraction of surface atoms and improve the metal-support interface. In this work, we employ a solvent/ligand/counterion-free meth...

    Tom Burwell, Madasamy Thangamuthu, Gazi N. Aliev in Communications Chemistry (2024)

  19. Article

    Open Access

    Rationally seeded computational protein design of ɑ-helical barrels

    Computational protein design is advancing rapidly. Here we describe efficient routes starting from validated parallel and antiparallel peptide assemblies to design two families of α-helical barrel proteins wit...

    Katherine I. Albanese, Rokas Petrenas, Fabio Pirro in Nature Chemical Biology (2024)

  20. Article

    Open Access

    Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria

    Bacteria have evolved resistance to nearly all known antibacterials, emphasizing the need to identify antibiotics that operate via novel mechanisms. Here we report a class of allosteric inhibitors of DNA gyras...

    Alexander T. Bakker, Ioli Kotsogianni, Mariana Avalos, Jeroen M. Punt in Nature Chemistry (2024)

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