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Chapter
Growth Activation in Adult Rat Hepatocytes
The hepatocytes in normal adult rats are in a state of quiescence, or G0. They retain the capacity to proliferate, however, and re-enter the cell cycle in partial synchrony, responding vigorously to 2/3 hepatecto...
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Chapter
Effect of Acute and Chronic Ethanol Intoxication on Hepatic Regeneration
We studied the effects of acute and chronic ethanol feeding on hepatic regeneration in rats following partial hepatectomy and toxic liver injury produced by D-galactosamine. Ethanol, when administered as a sin...
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Chapter and Conference Paper
Combined Influence of Insulin and Glucagon Upon Hepatocytes in Rats with Liver Loss or Viral Injury
Insulin and glucagon act in synergy to promote hepatic regeneration in eviscerated rats and to enhance survival in mice with viral hepatitis. Relatively low doses of insulin and high doses of glucagon are requ...