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Article
Influence of surgical trauma on the mRNA expression of sex hormone receptors in PBMCs in male and female patients
Gender-specific immune responses have been found after trauma-hemorrhage. Male and female sex hormones seem to be responsible for this gender dimorphism. Alterations in sex hormone receptor expression in mice ...
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Chapter and Conference Paper
Adjuvante therapeutische Vakzinierung beim Lungenkarzinom: erste Ergebnisse einer klinischen Pilotstudie mit autologer Tumorzell-Impfung nach Lymphopenie-Induktion und Rekonstitution mit autologen T Lymphozyten
Introduction: Given the considerable toxicity and modest benefit of adjuvant chemotherapy for non-small cell lung cancer (NSCLC), there is clearly a need for new treatment modalities in the adjuv...
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Chapter and Conference Paper
Einfluss von chirurgischem Trauma auf die Expression von Steroidhormonrezeptoren in PBMCs bei Patienten
Background: Animal experiments demonstrate a gender-specific immune response following trauma and hemorrhagic shock. In this respect, male (immunosuppressive) and female (immunoprotective) sex hormones have been ...
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Chapter and Conference Paper
Die Chemokine RANTES, MIP-1α und MIP-1ß spielen eine entscheidende Rolle bei T-Zell vermittelter Tumorregression
Introduction: Understanding the mechanisms involved in T-cell-mediated tumor regression is critical to develop and improve immunotherapy trials. Recently we could show that mice could be cured of e...
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Chapter and Conference Paper
Die T-Zell Polarisierung (TH1/TH2) Tumorvakzin drainierender Lymphozyten korreliert mit der Immunogenität des Tumors
Previously we have shown that vaccination with the poorly immunogenic B16BL6 (D5) melanoma elicits a non protective type 2 immune response in the tumor vaccine draining lymph nodes (TVDLN) of C57BL/6 mice. Her...
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Chapter and Conference Paper
Die Chemokine RANTES, KC und MCP-1 spielen eine mögliche Rolle bei T-Zell vermittelter Tumorregression
Understanding the mechanisms involved in T-cell mediated tumor regression is critical to develop and improve immunotherapy trials. Recently we reported that adoptively transferred tumor-specific effector T-cel...