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Chapter
Nutrition and Welfare
The horse is a social species living in herds and spending the majority of its time roaming and foraging in a diverse and seasonally-varying environment. As a non-ruminant herbivore it is well suited to a high...
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Article
Antidiuretic hormone infusion reduces taurine and NaCl-induced hypernatremia in the rats
Rats drinking taurine and hypertonic saline (T + S) develop severe hypernatremia, but rats drinking either T or S alone do not. One hypothesis for this disruption of homeostasis is that the T + S combination i...
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Chapter
Estrogen and Antiestrogen Resistance in Human Breast Cancer Cell Lines
Despite nearly a century of awareness of the efficacy of various kinds of endocrine therapies in the management of patients with metastatic breast cancer, many facets of the mechanisms whereby hormones influen...
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Article
Evidence for a neuronal release of isotopically labelled γ-amino-n-butyric acid (GABA) from the rat dorsal medulla in vivo
High potassium and electrical stimulation consistently increase efflux of labelled GABA from the in vivo superfused rat dorsal medulla in a calcium-dependent fashion. The depolarizing alkaloid, veratridine, al...
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Article
Comparison of bicyclic phosphorous esters with bicuculline and picrotoxin as antagonists of presynaptic inhibition in the rat cuneate nucleus
The effects of 2 of a series of bicyclic phosphorous esters, the ethyl (EPTBO) and isopropyl (IPTBO) compounds, were compared with those of the GABA antagonists, picrotoxin and bicuculline, on presynaptic inhi...
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Article
Isethionate may not be an inert substitute for extracellular chloride in the central nervous system
Replacement of extracellular chloride with isethionate or methylsulphate causes an increased efflux of 1-[14C]-GABA from the in vivo superfused rat cuneate nucleus. This raises the question of the suitability of ...
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Article
Concerning the ionic basis of presynaptic inhibition
The superfused rat cuneate nucleus has been used to investigate the sensitivity of primary afferent terminals and of evoked primary afferent depolarization (PAD) to alterations in extracellular K+ and Cl− ion lev...
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Article
IS2, a genetic element for turn-off and turn-on of gene activity in E. coli
Genetic analysis of the constitutive revertants of the IS2 mutation 308 located in the control region of the gal operon on the bacterial chromosome suggests that the constitutive expression of the gal genes might...