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    Article

    Serum elevations of soluble Fas (CD95/Apo-I) concur in deregulating T cell apoptosis during active lupus disease

    Apoptosis is deregulated in active systemic lupus erythematosus and Fas is overexpressed by T cells, although the role of its soluble form (sFas) is unclear. We have explored both the biological significance ...

    F. Silvestris, R. C. Williams, N. Calvani in Clinical and Experimental Medicine (2002)

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    Sequential use of sorafenib and sunitinib in advanced renal cell carcinoma: does the order of sequencing matter?

    To investigate the sequential use of two tyrosine-kinase inhibitors (TKI), sorafenib (SOR) and sunitinib (SUN), in advanced renal carcinoma. We retrospectively analyzed the clinical outcome of 33 patients who ...

    N. Calvani, F. Morelli, S. Leo, L. Orlando, L. Lombardi, A. Gnoni in Medical Oncology (2012)

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    When less is better: the safety and efficacy of reduced intensity gemcitabine in a difficult patient population with advanced non-small-cell lung cancer

    Treatment of elderly or poor performance status (PS) patients with advanced non-small-cell lung cancer (NSCLC) is a debated topic. To evaluate the efficacy of a modified schedule of gemcitabine, 59 patients un...

    A. Nacci, N. Calvani, P. Rizzo, P. Fedele, L. Orlando, P. Schiavone in Medical Oncology (2013)