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Plk1 phosphorylation of Numb leads to impaired DNA damage response
Although Numb is well-recognized as a cell-fate determinant in stem/progenitor cells, accumulating evidence supports that Numb also has a critical role in adult tissues and cancers, in particular, in the conte...
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Article
Open AccessESICM LIVES 2016: part one
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The incidence of unexplained visual loss following removal of silicone oil
To assess the incidence and clinical features of unexpected visual loss after removal of silicone oil (ROSO).
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Article
Erratum to: Oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA), a hidden resistant mechanism among clinically significant isolates in the Wessex region/UK
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Oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA), a hidden resistant mechanism among clinically significant isolates in the Wessex region/UK
Methicillin-resistant Staphylococcus aureus (MRSA) is defined as S. aureus genetically having the mecA or mecC genes or phenotypically showing minimum inhibitory concentration (MIC) of oxacillin higher than 2 mg/...
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Article
Open AccessMicroRNA theragnostics for the clinical management of multiple myeloma
Theragnostics represent cutting-edge, multi-disciplinary strategies that combine diagnostics with therapeutics in order to generate personalized therapies that improve patient outcome. In oncology, the approac...
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Pilot randomised controlled trial of face-down positioning following macular hole surgery
This was a pilot randomised controlled trial (RCT) to investigate the effect of post-operative face-down positioning on the outcome of macular hole surgery and to inform the design of a larger definitive study.
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Open AccessCommunity-acquired methicillin-resistant Staphylococcus auereus in a Malaysian tertiary centre in year 2009
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Article
Is there a correlation between 18F-FDG-PET standardized uptake value, T-classification, histological grading and the anatomic subsites in newly diagnosed squamous cell carcinoma of the head and neck?
18F-Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET)/CT imaging of squamous cell carcinoma of the head and neck (HNSCC) renders the possibility to study metabolic tumor activity by....
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Article
Spontaneous pneumomediastinum: a rare complication of acute asthma
Pneumomediastinum and subcutaneous emphysema are rare complications of acute asthma. If pneumomediastinum occurs it can cause compression on major vessels in the mediastinum and neck and can lead to low blood ...
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Article
Risk of Malignancy in Resected Cystic Tumors of the Pancreas ≤3 cm in Size: Is it Safe to Observe Asymptomatic Patients? A Multi-institutional Report
Recent international consensus guidelines propose that cystic pancreatic tumors less than 3 cm in size in asymptomatic patients with no radiographic features concerning for malignancy are safe to observe; howe...
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Article
Current opinion on treatment of asymptomatic retinal detachments
To determine the current opinion of vitreoretinal consultants in the UK on the treatment of asymptomatic retinal detachments.
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Intraocular surgery for optic nerve disorders
This article discusses two current indications for intraocular surgery for optic nerve conditions. The first topic is macular detachment in association with congenital optic disc pit, and includes a review of ...