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  1. Article

    Open Access

    Two-year post-distraction cartilage-related structural improvement is accompanied by increased serum full-length SIRT1

    Previously, fragments from Sirtuin 1 (SIRT1) were identified in preclinical and clinical samples to display an increase in serum levels for N-terminal (NT) SIRT1 vs. C-terminal (CT) SIRT1, indicative of early ...

    Miya Marco, Mylène Jansen, Goran van der Weiden, Eli Reich… in Arthritis Research & Therapy (2024)

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  2. Article

    Open Access

    Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort

    The IMI-APPROACH cohort is an exploratory, 5-centre, 2-year prospective follow-up study of knee osteoarthritis (OA). Aim was to describe baseline multi-tissue semiquantitative MRI evaluation of index knees and...

    Frank W. Roemer, Mylène Jansen, Anne C. A. Marijnissen… in BMC Musculoskeletal Disorders (2022)

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